Geometric Dependence of 3D Collective Cancer Invasion

Metastasis of mesenchymal tumor cells is traditionally considered as a single-cell process. Here, we report an emergent collective phenomenon in which the dissemination rate of mesenchymal breast cancer cells from three-dimensional tumors depends on the tumor geometry. Combining experimental measure...

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Veröffentlicht in:	Biophysical journal 2020-03, Vol.118 (5), p.1177-1182
Hauptverfasser:	Kim, Jihan, Zheng, Yu, Alobaidi, Amani A., Nan, Hanqing, Tian, Jianxiang, Jiao, Yang, Sun, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Cell Movement Extracellular Matrix Humans Neoplasm Invasiveness
Online-Zugang:	Volltext
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