CRISPLD1: a novel conserved target in the transition to human heart failure

Heart failure is a major health problem worldwide with a significant morbidity and mortality rate. Although studied extensively in animal models, data from patients at the compensated disease stage are lacking. We sampled myocardium biopsies from aortic stenosis patients with compensated hypertrophy...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Basic research in cardiology 2020-05, Vol.115 (3), p.27, Article 27
Hauptverfasser:	Khadjeh, Sara, Hindmarsh, Vanessa, Weber, Frederike, Cyganek, Lukas, Vidal, Ramon O., Torkieh, Setare, Streckfuss-Bömeke, Katrin, Lbik, Dawid, Tiburcy, Malte, Mohamed, Belal A., Bonn, Stefan, Toischer, Karl, Hasenfuss, Gerd
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animal models Animals Aorta Aortic stenosis Aortic Valve Stenosis - complications Aortic Valve Stenosis - genetics Aortic Valve Stenosis - metabolism Apoptosis Biopsy Calcium - metabolism Calcium ions Calcium Signaling Calcium signalling Cardiology Cardiomyocytes Cell Adhesion Molecules - chemistry Cell Adhesion Molecules - deficiency Cell Adhesion Molecules - genetics Cell Adhesion Molecules - metabolism Comparative analysis Congestive heart failure Conserved Sequence CRISPR Down-Regulation Evolution, Molecular Female Gene expression Gene regulation Genes Heart failure Heart Failure - complications Heart Failure - genetics Heart Failure - metabolism Homology Human influences Humans Hypertrophy Induced Pluripotent Stem Cells - cytology Ion channels Male Medicine Medicine & Public Health Mice Morbidity Myocardium Myocardium - metabolism Myocytes, Cardiac - cytology Myocytes, Cardiac - metabolism Original Contribution Pluripotency Stem cells Stenosis Therapeutic applications Toxins Transcriptome Transforming Growth Factor beta - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!