Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination

During development, neural progenitors change their competence states over time to sequentially generate different types of neurons and glia. Several cascades of temporal transcription factors (tTFs) have been discovered in Drosophila to control the temporal identity of neuroblasts, but the temporal...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2020-03, Vol.117 (9), p.5028-5038
Hauptverfasser:	Houben, Evelien, Janssens, Kris, Hermans, Doryssa, Vandooren, Jennifer, Van den Haute, Chris, Schepers, Melissa, Vanmierlo, Tim, Lambrichts, Ivo, van Horssen, Jack, Baekelandt, Veerle, Opdenakker, Ghislain, Baron, Wia, Broux, Bieke, Slaets, Helena, Hellings, Niels
Format:	Artikel
Sprache:	eng
Schlagworte:	Astrocytes Axons Biological Sciences Brain damage Cell differentiation Central nervous system Demyelination Disorders Glial stem cells Inhibitors Interleukin 6 Multiple sclerosis Myelin Myelination Oligodendrocytes Oncostatin M Tissue inhibitor of metalloproteinase 1
Online-Zugang:	Volltext
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