Oncomir MicroRNA-346 Is Upregulated in Colons of Patients With Primary Sclerosing Cholangitis

Primary sclerosing cholangitis (PSC) is a cholestatic liver disorder that is frequently associated with ulcerative colitis (UC). Patients with PSC and UC (PSC-UC) have a higher risk of colorectal neoplasia compared with patients with UC. The oncogenic properties of microRNA-346 (miR-346) have been r...

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Veröffentlicht in:	Clinical and translational gastroenterology 2020-01, Vol.11 (1), p.e00112-e00112
Hauptverfasser:	Kempinska-Podhorodecka, Agnieszka, Blatkiewicz, Malgorzata, Wunsch, Ewa, Krupa, Lukasz, Gutkowski, Krzysztof, Milkiewicz, Piotr, Milkiewicz, Malgorzata
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies Caco-2 Cells Cancer Case-Control Studies Cell cycle Cholagogues and Choleretics - pharmacology Cholangitis Cholangitis, Sclerosing - complications Cholangitis, Sclerosing - genetics Cholangitis, Sclerosing - metabolism Colitis, Ulcerative - complications Colitis, Ulcerative - genetics Colitis, Ulcerative - metabolism Colon Colon - metabolism Colon, Ascending Colon, Sigmoid Colonoscopy Colorectal cancer Colorectal Neoplasms - genetics Cyclin-Dependent Kinase Inhibitor p27 - drug effects Cyclin-Dependent Kinase Inhibitor p27 - genetics Female Gene expression Gene Expression Regulation Hep G2 Cells Humans Inflammatory bowel disease Kinases Laboratories Male MicroRNAs MicroRNAs - drug effects MicroRNAs - genetics Middle Aged Pathogenesis Patients Proteins Receptors, Calcitriol - drug effects Receptors, Calcitriol - genetics RNA, Ribosomal, 18S - genetics Software Tumor Necrosis Factor-alpha - drug effects Tumor Necrosis Factor-alpha - genetics Tumor necrosis factor-TNF Tumors Up-Regulation Ursodeoxycholic Acid - pharmacology Vitamin D Young Adult
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