The role of the endothelial glycocalyx in advanced age and cardiovascular disease

•The endothelial glycocalyx is a gel-like structure that lines the endothelium.•In advanced age and cardiovascular disease (CVD), the glycocalyx is deteriorated.•An intact glycocalyx is critical to a properly functioning endothelium.•Glycocalyx deterioration may initiate age-related CVD pathology. T...

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Veröffentlicht in:	Current opinion in pharmacology 2019-04, Vol.45, p.66-71
Hauptverfasser:	Machin, Daniel R, Phuong, Tam TT, Donato, Anthony J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Cardiovascular Diseases - physiopathology Endothelium, Vascular - physiology Glycocalyx - physiology Humans
Online-Zugang:	Volltext
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