Extracellular vesicle-miRNAs as liquid biopsy biomarkers for disease identification and prognosis in metastatic colorectal cancer patients

Disseminated disease is present in ≈50% of colorectal cancer patients upon diagnosis, being responsible for most of cancer deaths. Addition of biological drugs, as Bevacizumab, to chemotherapy, has increased progression free survival and overall survival of metastatic colorectal cancer (mCRC) patien...

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Veröffentlicht in:	Scientific reports 2020-03, Vol.10 (1), p.3974, Article 3974
Hauptverfasser:	de Miguel Pérez, Diego, Rodriguez Martínez, Alba, Ortigosa Palomo, Alba, Delgado Ureña, Mayte, Garcia Puche, Jose Luis, Robles Remacho, Agustín, Exposito Hernandez, José, Lorente Acosta, Jose Antonio, Ortega Sánchez, Francisco Gabriel, Serrano, Ma Jose
Format:	Artikel
Sprache:	eng
Schlagworte:	38 38/77 45/90 631/67/1857 692/4028/67/1504/1885 96 Bevacizumab Biomarkers Biomarkers, Tumor - metabolism Biopsy Cancer Carcinoembryonic antigen Chemotherapy Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnosis Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Diagnosis Disease-Free Survival Extracellular vesicles Extracellular Vesicles - genetics Female Heterogeneity Humanities and Social Sciences Humans Male Medical prognosis Metastases Metastasis MicroRNAs MicroRNAs - metabolism Middle Aged miRNA Monoclonal antibodies multidisciplinary Neoplasm Metastasis Prognosis Science Science (multidisciplinary) Targeted cancer therapy
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