Dual dynamics of mitochondrial permeability transition pore opening

Mitochondria play an essential role in bioenergetics and cellular Ca 2 + handling. The mitochondrial permeability transition pore (mPTP) is a non-specific channel located in the inner mitochondrial membrane. Long-lasting openings of the pore allow the rapid passage of ions and large molecules, which...

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Veröffentlicht in:	Scientific reports 2020-03, Vol.10 (1), p.3924-3924, Article 3924
Hauptverfasser:	Wacquier, Benjamin, Combettes, Laurent, Dupont, Geneviève
Format:	Artikel
Sprache:	eng
Schlagworte:	631/114/2397 631/80/86/1999 Bioenergetics Calcium - metabolism Cell death Cellular Biology Computer applications Conductance Homeostasis Humanities and Social Sciences Life Sciences Membrane permeability Membrane Potential, Mitochondrial Mitochondrial Membrane Transport Proteins - chemistry Mitochondrial Membrane Transport Proteins - metabolism Mitochondrial Permeability Transition Pore Models, Biological multidisciplinary Permeability Protein Conformation Science Science (multidisciplinary) Subcellular Processes
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