Synaptic Elimination in Neurological Disorders

Synapses are well known as the main structures responsible for transmitting information through the release and recognition of neurotransmitters by pre- and post-synaptic neurons. These structures are widely formed and eliminated throughout the whole lifespan via processes termed synaptogenesis and...

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Veröffentlicht in:	Current neuropharmacology 2019-01, Vol.17 (11), p.1071-1095
Hauptverfasser:	Cardozo, Pablo L, de Lima, Izabella B Q, Maciel, Esther M A, Silva, Nathália C, Dobransky, Tomas, Ribeiro, Fabíola M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - physiopathology Alzheimer's disease Animal models Animals Complement Activation - physiology Complement component C3 Dendritic spines Humans Life span Mental disorders Microglia Microglial cells Multiple sclerosis Multiple Sclerosis - physiopathology Neural networks Neurodegenerative diseases Neurological diseases Neurological disorders Neuronal Plasticity - physiology Neurotransmitters Schizophrenia Schizophrenia - physiopathology Synaptic transmission Synaptogenesis
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