The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts

Exposure to cigarette smoke (CS) causes detrimental health effects, increasing the risk of cardiovascular, pulmonary diseases and carcinogenesis in exposed individuals. The impact of CS on Inflammatory Bowel Disease (IBD) has been established by a number of epidemiological and clinical studies. In f...

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Veröffentlicht in:	Scientific reports 2020-03, Vol.10 (1), p.3829, Article 3829
Hauptverfasser:	Lo Sasso, Giuseppe, Phillips, Blaine W., Sewer, Alain, Battey, James N. D., Kondylis, Athanasios, Talikka, Marja, Titz, Bjoern, Guedj, Emmanuel, Peric, Dariusz, Bornand, David, Dulize, Remi, Merg, Celine, Corciulo, Maica, Ouadi, Sonia, Yanuar, Rendy, Tung, Ching Keong, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia
Format:	Artikel
Sprache:	eng
Schlagworte:	38/61 45/22 45/23 631/337 64 64/60 692/4020/1503 692/4020/2199 96/21 Animals Carcinogenesis Cardiovascular diseases Cigarette smoke Cigarette smoking Cigarettes Colitis - chemically induced Colitis - immunology Colitis - microbiology Colon Comparative analysis Crohn's disease Dextran Dextran Sulfate - pharmacology Disease Drug addiction Dysbacteriosis Epidemiology Gene expression Health risks Humanities and Social Sciences Immunomodulation Inflammatory bowel disease Inflammatory bowel diseases Intestinal microflora Intestine Lung diseases Male Metagenomics Mice Mice, Inbred C57BL Microbiomes Microbiota - drug effects Molecular modelling multidisciplinary Science Science (multidisciplinary) Smoke - adverse effects Smoking Sodium sulfate Tobacco Tobacco Products - adverse effects Ulcerative colitis
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