Cerebrovascular Reactivity Is a Main Determinant of White Matter Hyperintensity Progression in CADASIL

Basal total cerebral blood flow (TCBF) and cerebrovascular reactivity (CVR) are assumed to play an important role in the pathophysiology of small-vessel disease. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a unique monogenetic model to stud...

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Veröffentlicht in:	American journal of neuroradiology : AJNR 2009-06, Vol.30 (6), p.1244-1247
Hauptverfasser:	Liem, M.K, Lesnik Oberstein, S.A.J, Haan, J, Boom, R.v.d, Ferrari, M.D, Buchem, M.A.v, Grond, J.v.d
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Brain CADASIL - complications CADASIL - pathology Cerebrovascular Disorders - complications Cerebrovascular Disorders - diagnosis Disease Progression Female Humans Investigative techniques, diagnostic techniques (general aspects) Magnetic Resonance Imaging - methods Male Medical sciences Middle Aged Nerve Fibers, Myelinated - pathology Nervous system Radiodiagnosis. Nmr imagery. Nmr spectrometry Reproducibility of Results Sensitivity and Specificity
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