Nuclear PARPs and genome integrity

Effective maintenance and stability of our genomes is essential for normal cell division, tissue homeostasis, and cellular and organismal fitness. The processes of chromosome replication and segregation require continual surveillance to insure fidelity. Accurate and efficient repair of DNA damage pr...

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Veröffentlicht in:	Genes & development 2020-03, Vol.34 (5-6), p.285-301
Hauptverfasser:	Azarm, Kameron, Smith, Susan
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Cell Nucleus - enzymology DNA Repair DNA Replication Genomic Instability - physiology Humans Poly(ADP-ribose) Polymerases - metabolism Special Section: Review Structure-Activity Relationship
Online-Zugang:	Volltext
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