MCL1 binding to the reverse BH3 motif of P18INK4C couples cell survival to cell proliferation

Commitment to cell cycle entry and cellular duplication is a tightly coordinated and regulated process. Once initiated, a series of multiple checkpoints ensure both accurate genomic replication and chromosomal separation. In the event of unsuccessful cell division, parallel pathways exist that induc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell death & disease 2020-02, Vol.11 (2), p.156-156, Article 156
Hauptverfasser:	Whitaker, Robert H., Placzek, William J.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/2 13/31 631/45/612 631/80/641/2187 631/80/82/23 631/80/86 82/1 82/80 82/83 Ankyrins Antibodies Apoptosis Apoptosis Regulatory Proteins - metabolism Biochemistry Biomedical and Life Sciences Cancer Cell Biology Cell Culture Cell cycle Cell death Cell division Cell growth Cell Line, Tumor Cell proliferation Cell Proliferation - physiology Cell survival Cell Survival - physiology Cyclin-dependent kinase 4 Cyclin-Dependent Kinase Inhibitor p18 - metabolism Humans Immunology Life Sciences Mcl-1 protein Myeloid Cell Leukemia Sequence 1 Protein - metabolism Peptide Fragments - metabolism Proteins Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-bcl-2 - metabolism Regulatory proteins Retina Retinoblastoma
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!