Identification of significant gene biomarkers of low back pain caused by changes in the osmotic pressure of nucleus pulposus cells

The incidence of intervertebral disc (IVD) degeneration disease, caused by changes in the osmotic pressure of nucleus pulposus (NP) cells, increases with age. In general, low back pain is associated with IVD degeneration. However, the mechanism and molecular target of low back pain have not been elu...

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Veröffentlicht in:	Scientific reports 2020-02, Vol.10 (1), p.3708-3708, Article 3708
Hauptverfasser:	Zhao, Changsong, Quan, Xuemin, He, Jie, Zhao, Rugang, Zhang, Yao, Li, Xin, Sun, Sheng, Ma, Rui, Zhang, Qiang
Format:	Artikel
Sprache:	eng
Schlagworte:	13 38/61 38/77 45 692/4017 692/53 Back pain Bioinformatics Biomarkers Correlation analysis CXCL13 protein Degeneration Gene Expression Genetic Markers Humanities and Social Sciences Humans Intervertebral Disc - chemistry Intervertebral Disc - metabolism Intervertebral Disc - surgery Intervertebral discs Low back pain Low Back Pain - genetics Low Back Pain - metabolism Low Back Pain - surgery multidisciplinary Neural networks Nucleus pulposus Nucleus Pulposus - chemistry Nucleus Pulposus - metabolism Osmotic Pressure Proteins - genetics Proteins - metabolism Science Science (multidisciplinary) Surgery
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