Multi-omics characterization of molecular features of gastric cancer correlated with response to neoadjuvant chemotherapy

Neoadjuvant chemotherapy is a common treatment for patients with gastric cancer. Although its benefits have been demonstrated, neoadjuvant chemotherapy is underutilized in gastric cancer management, because of the lack of biomarkers for patient selection and a limited understanding of resistance mec...

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Veröffentlicht in:	Science advances 2020-02, Vol.6 (9), p.eaay4211
Hauptverfasser:	Li, Ziyu, Gao, Xiangyu, Peng, Xinxin, May Chen, Mei-Ju, Li, Zhe, Wei, Bin, Wen, Xianzi, Wei, Baoye, Dong, Yu, Bu, Zhaode, Wu, Aiwen, Wu, Qi, Tang, Lei, Li, Zhongwu, Liu, Yiqiang, Zhang, Li, Jia, Shuqin, Zhang, Lianhai, Shan, Fei, Zhang, Ji, Wu, Xiaojiang, Ji, Xin, Ji, Ke, Wu, Xiaolong, Shi, Jinyao, Xing, Xiaofang, Wu, Jianmin, Lv, Guoqing, Shen, Lin, Ji, Xuwo, Liang, Han, Ji, Jiafu
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - genetics Cancer Carrier Proteins - genetics Female Human Genetics Humans Intercellular Signaling Peptides and Proteins Male Middle Aged Neoadjuvant Therapy Proto-Oncogene Proteins c-mdm2 - genetics Proto-Oncogene Proteins c-myc - genetics RNA-Seq SciAdv r-articles Stomach Neoplasms - genetics Stomach Neoplasms - pathology Stomach Neoplasms - therapy Whole Genome Sequencing
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