Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling

Previously, DNA damage sensing, repairing and signaling machineries were thought to mainly suppress genomic instability in response to genotoxic stress. Emerging evidence indicates a crosstalk between DNA repair machinery and the immune system. In this chapter, we attempt to decipher the molecular c...

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Veröffentlicht in:	Advances in protein chemistry and structural biology 2019, Vol.115, p.297-324
Hauptverfasser:	Mukherjee, Shibani, Abdisalaam, Salim, Bhattacharya, Souparno, Srinivasan, Kalayarasan, Sinha, Debapriya, Asaithamby, Aroumougame
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA - genetics DNA - immunology DNA Damage - immunology DNA Repair - immunology Humans Signal Transduction - immunology
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