Effect of Hydrocortisone vs Pasireotide on Pancreatic Surgery Complications in Patients With High Risk of Pancreatic Fistula: A Randomized Clinical Trial

IMPORTANCE: Both hydrocortisone and pasireotide have been shown in randomized clinical trials to be effective in reducing postoperative complications of pancreatic surgery, but to date no randomized clinical trial has evaluated the effectiveness of pasireotide compared with hydrocortisone. OBJECTIVE...

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Veröffentlicht in:	Archives of surgery (Chicago. 1960) 2020-04, Vol.155 (4), p.291-298
Hauptverfasser:	Tarvainen, Timo, Sirén, Jukka, Kokkola, Arto, Sallinen, Ville
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Anti-Inflammatory Agents - therapeutic use Clinical outcomes Clinical trials Female Finland Hormones - therapeutic use Humans Hydrocortisone - therapeutic use Intention to Treat Analysis Male Middle Aged Online First Original Investigation Pancreas Pancreatectomy Pancreatic cancer Pancreatic Fistula - prevention & control Postoperative Complications - prevention & control Postoperative period Prospective Studies Side effects Somatostatin - analogs & derivatives Somatostatin - therapeutic use Steroids
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