Increased Visceral Adipose Tissue Without Weight Retention at 59 Weeks Postpartum
Objective This study aimed to determine whether controlling maternal gestational weight gain (GWG) influences adipose tissue distribution at 1 year postpartum. Methods Women with overweight or obesity (n = 210, BMI ≥ 25 or ≥ 30) were randomized to a lifestyle intervention (LI) designed to control GW...
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| Veröffentlicht in: | Obesity (Silver Spring, Md.) Md.), 2020-03, Vol.28 (3), p.552-562 |
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| container_title | Obesity (Silver Spring, Md.) |
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| creator | Janumala, Isaiah Toro‐Ramos, Tatiana Widen, Elizabeth Rosenn, Barak Crane, Janet Horowitz, Michelle Lin, Susan Gidwani, Sonia Paley, Charles Thornton, John C. Pi‐Sunyer, F. Xavier Gallagher, Dympna |
| description | Objective
This study aimed to determine whether controlling maternal gestational weight gain (GWG) influences adipose tissue distribution at 1 year postpartum.
Methods
Women with overweight or obesity (n = 210, BMI ≥ 25 or ≥ 30) were randomized to a lifestyle intervention (LI) designed to control GWG or to usual obstetrical care (UC). Measures included anthropometry, whole‐body magnetic resonance imaging for visceral (VAT), intermuscular, and subcutaneous adipose tissue, and cardiometabolic risk factors in pregnancy (15 and 35 weeks) and after delivery (15 and 59 weeks).
Results
Baseline (15 weeks) characteristics were similar (mean [SD]: age, 33.8 [4.3] years; weight, 81.9 [13.7] kg; BMI, 30.4 [4.5]; gestational age at randomization, 14.9 [0.8] weeks). LI had less GWG (1.79 kg; P = 0.003) and subcutaneous adipose tissue gain at 35 weeks gestation (P |
| doi_str_mv | 10.1002/oby.22736 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7042094</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2352632660</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4436-6e1907977c093eb12bbca3a34d7c132b7289cf8da9627d0f9bb5221150af4dc23</originalsourceid><addsrcrecordid>eNp1kdFOFDEUhhsjEQQvfAHTxBu9WDhtZ9rpjQkSRBISlKDoVdPpnGGLs9Ol7Uj27S0sbtTEq570fPnytz8hLxnsMwB-ENrVPudKyCdkh2kBMyX0t6ebuWHb5HlKNwCVhJo9I9uCgwDN2A75fDq6iDZhR7_65DDagR52fhkS0kuf0oT0yud5mDK9Qn89z_QCM47Zh5HaTGtdrvFHop9Cyksb87TYI1u9HRK-eDx3yZcPx5dHH2dn5yenR4dnM1dVQs4kMg1KK-VAC2wZb1tnhRVVpxwTvFW80a5vOqslVx30um1rzhmrwfZV57jYJe_W3uXULrBzJVQJb5bRL2xcmWC9-Xsz-rm5Dj-NgoqDrorgzaMghtsJUzaL-x8YBjtimJLhouZScCmhoK__QW_CFMfyvEI1Vd0I0chCvV1TLoaUIvabMAzMfVGmFGUeiirsqz_Tb8jfzRTgYA3c-QFX_zeZ8_ff18pfTqCc6Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2384583386</pqid></control><display><type>article</type><title>Increased Visceral Adipose Tissue Without Weight Retention at 59 Weeks Postpartum</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Wiley Free Content</source><creator>Janumala, Isaiah ; Toro‐Ramos, Tatiana ; Widen, Elizabeth ; Rosenn, Barak ; Crane, Janet ; Horowitz, Michelle ; Lin, Susan ; Gidwani, Sonia ; Paley, Charles ; Thornton, John C. ; Pi‐Sunyer, F. Xavier ; Gallagher, Dympna</creator><creatorcontrib>Janumala, Isaiah ; Toro‐Ramos, Tatiana ; Widen, Elizabeth ; Rosenn, Barak ; Crane, Janet ; Horowitz, Michelle ; Lin, Susan ; Gidwani, Sonia ; Paley, Charles ; Thornton, John C. ; Pi‐Sunyer, F. Xavier ; Gallagher, Dympna</creatorcontrib><description>Objective
This study aimed to determine whether controlling maternal gestational weight gain (GWG) influences adipose tissue distribution at 1 year postpartum.
Methods
Women with overweight or obesity (n = 210, BMI ≥ 25 or ≥ 30) were randomized to a lifestyle intervention (LI) designed to control GWG or to usual obstetrical care (UC). Measures included anthropometry, whole‐body magnetic resonance imaging for visceral (VAT), intermuscular, and subcutaneous adipose tissue, and cardiometabolic risk factors in pregnancy (15 and 35 weeks) and after delivery (15 and 59 weeks).
Results
Baseline (15 weeks) characteristics were similar (mean [SD]: age, 33.8 [4.3] years; weight, 81.9 [13.7] kg; BMI, 30.4 [4.5]; gestational age at randomization, 14.9 [0.8] weeks). LI had less GWG (1.79 kg; P = 0.003) and subcutaneous adipose tissue gain at 35 weeks gestation (P < 0.01). UC postpartum weight (2.92 kg) was higher at 15 weeks but not different from baseline or LI at 59 weeks postpartum. Postpartum VAT increased from baseline in LI by 0.23 kg at 15 weeks and 0.55 kg at 59 weeks; in UC, it increased by 0.34 kg at 15 and 59 weeks. Intermuscular adipose tissue remained elevated in LI (0.22 kg) at 59 weeks. VAT was associated with several cardiometabolic risk factors at 59 weeks.
Conclusions
Despite no weight retention at 59 weeks postpartum, women had increased VAT by ~30%. Postpartum modifiable behaviors are warranted to lower the risk of VAT retention.</description><identifier>ISSN: 1930-7381</identifier><identifier>EISSN: 1930-739X</identifier><identifier>DOI: 10.1002/oby.22736</identifier><identifier>PMID: 32030911</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Abdomen ; Adult ; Age ; Body composition ; Body fat ; Cholesterol ; Diabetes ; Exercise ; Female ; Humans ; Hypotheses ; Intervention ; Intra-Abdominal Fat - physiopathology ; Lifestyles ; Magnetic resonance imaging ; Obesity ; Physical fitness ; Postpartum Period ; Pregnancy ; Retention ; Tumor necrosis factor-TNF ; Variables ; Whole Body Imaging - methods ; Womens health</subject><ispartof>Obesity (Silver Spring, Md.), 2020-03, Vol.28 (3), p.552-562</ispartof><rights>2020 The Obesity Society.</rights><rights>Copyright Blackwell Publishing Ltd. Mar 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4436-6e1907977c093eb12bbca3a34d7c132b7289cf8da9627d0f9bb5221150af4dc23</citedby><cites>FETCH-LOGICAL-c4436-6e1907977c093eb12bbca3a34d7c132b7289cf8da9627d0f9bb5221150af4dc23</cites><orcidid>0000-0003-1769-9754 ; 0000-0002-9574-6109</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Foby.22736$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Foby.22736$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,777,781,882,1412,1428,27905,27906,45555,45556,46390,46814</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32030911$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Janumala, Isaiah</creatorcontrib><creatorcontrib>Toro‐Ramos, Tatiana</creatorcontrib><creatorcontrib>Widen, Elizabeth</creatorcontrib><creatorcontrib>Rosenn, Barak</creatorcontrib><creatorcontrib>Crane, Janet</creatorcontrib><creatorcontrib>Horowitz, Michelle</creatorcontrib><creatorcontrib>Lin, Susan</creatorcontrib><creatorcontrib>Gidwani, Sonia</creatorcontrib><creatorcontrib>Paley, Charles</creatorcontrib><creatorcontrib>Thornton, John C.</creatorcontrib><creatorcontrib>Pi‐Sunyer, F. Xavier</creatorcontrib><creatorcontrib>Gallagher, Dympna</creatorcontrib><title>Increased Visceral Adipose Tissue Without Weight Retention at 59 Weeks Postpartum</title><title>Obesity (Silver Spring, Md.)</title><addtitle>Obesity (Silver Spring)</addtitle><description>Objective
This study aimed to determine whether controlling maternal gestational weight gain (GWG) influences adipose tissue distribution at 1 year postpartum.
Methods
Women with overweight or obesity (n = 210, BMI ≥ 25 or ≥ 30) were randomized to a lifestyle intervention (LI) designed to control GWG or to usual obstetrical care (UC). Measures included anthropometry, whole‐body magnetic resonance imaging for visceral (VAT), intermuscular, and subcutaneous adipose tissue, and cardiometabolic risk factors in pregnancy (15 and 35 weeks) and after delivery (15 and 59 weeks).
Results
Baseline (15 weeks) characteristics were similar (mean [SD]: age, 33.8 [4.3] years; weight, 81.9 [13.7] kg; BMI, 30.4 [4.5]; gestational age at randomization, 14.9 [0.8] weeks). LI had less GWG (1.79 kg; P = 0.003) and subcutaneous adipose tissue gain at 35 weeks gestation (P < 0.01). UC postpartum weight (2.92 kg) was higher at 15 weeks but not different from baseline or LI at 59 weeks postpartum. Postpartum VAT increased from baseline in LI by 0.23 kg at 15 weeks and 0.55 kg at 59 weeks; in UC, it increased by 0.34 kg at 15 and 59 weeks. Intermuscular adipose tissue remained elevated in LI (0.22 kg) at 59 weeks. VAT was associated with several cardiometabolic risk factors at 59 weeks.
Conclusions
Despite no weight retention at 59 weeks postpartum, women had increased VAT by ~30%. Postpartum modifiable behaviors are warranted to lower the risk of VAT retention.</description><subject>Abdomen</subject><subject>Adult</subject><subject>Age</subject><subject>Body composition</subject><subject>Body fat</subject><subject>Cholesterol</subject><subject>Diabetes</subject><subject>Exercise</subject><subject>Female</subject><subject>Humans</subject><subject>Hypotheses</subject><subject>Intervention</subject><subject>Intra-Abdominal Fat - physiopathology</subject><subject>Lifestyles</subject><subject>Magnetic resonance imaging</subject><subject>Obesity</subject><subject>Physical fitness</subject><subject>Postpartum Period</subject><subject>Pregnancy</subject><subject>Retention</subject><subject>Tumor necrosis factor-TNF</subject><subject>Variables</subject><subject>Whole Body Imaging - methods</subject><subject>Womens health</subject><issn>1930-7381</issn><issn>1930-739X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kdFOFDEUhhsjEQQvfAHTxBu9WDhtZ9rpjQkSRBISlKDoVdPpnGGLs9Ol7Uj27S0sbtTEq570fPnytz8hLxnsMwB-ENrVPudKyCdkh2kBMyX0t6ebuWHb5HlKNwCVhJo9I9uCgwDN2A75fDq6iDZhR7_65DDagR52fhkS0kuf0oT0yud5mDK9Qn89z_QCM47Zh5HaTGtdrvFHop9Cyksb87TYI1u9HRK-eDx3yZcPx5dHH2dn5yenR4dnM1dVQs4kMg1KK-VAC2wZb1tnhRVVpxwTvFW80a5vOqslVx30um1rzhmrwfZV57jYJe_W3uXULrBzJVQJb5bRL2xcmWC9-Xsz-rm5Dj-NgoqDrorgzaMghtsJUzaL-x8YBjtimJLhouZScCmhoK__QW_CFMfyvEI1Vd0I0chCvV1TLoaUIvabMAzMfVGmFGUeiirsqz_Tb8jfzRTgYA3c-QFX_zeZ8_ff18pfTqCc6Q</recordid><startdate>202003</startdate><enddate>202003</enddate><creator>Janumala, Isaiah</creator><creator>Toro‐Ramos, Tatiana</creator><creator>Widen, Elizabeth</creator><creator>Rosenn, Barak</creator><creator>Crane, Janet</creator><creator>Horowitz, Michelle</creator><creator>Lin, Susan</creator><creator>Gidwani, Sonia</creator><creator>Paley, Charles</creator><creator>Thornton, John C.</creator><creator>Pi‐Sunyer, F. Xavier</creator><creator>Gallagher, Dympna</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-1769-9754</orcidid><orcidid>https://orcid.org/0000-0002-9574-6109</orcidid></search><sort><creationdate>202003</creationdate><title>Increased Visceral Adipose Tissue Without Weight Retention at 59 Weeks Postpartum</title><author>Janumala, Isaiah ; Toro‐Ramos, Tatiana ; Widen, Elizabeth ; Rosenn, Barak ; Crane, Janet ; Horowitz, Michelle ; Lin, Susan ; Gidwani, Sonia ; Paley, Charles ; Thornton, John C. ; Pi‐Sunyer, F. Xavier ; Gallagher, Dympna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4436-6e1907977c093eb12bbca3a34d7c132b7289cf8da9627d0f9bb5221150af4dc23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Abdomen</topic><topic>Adult</topic><topic>Age</topic><topic>Body composition</topic><topic>Body fat</topic><topic>Cholesterol</topic><topic>Diabetes</topic><topic>Exercise</topic><topic>Female</topic><topic>Humans</topic><topic>Hypotheses</topic><topic>Intervention</topic><topic>Intra-Abdominal Fat - physiopathology</topic><topic>Lifestyles</topic><topic>Magnetic resonance imaging</topic><topic>Obesity</topic><topic>Physical fitness</topic><topic>Postpartum Period</topic><topic>Pregnancy</topic><topic>Retention</topic><topic>Tumor necrosis factor-TNF</topic><topic>Variables</topic><topic>Whole Body Imaging - methods</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Janumala, Isaiah</creatorcontrib><creatorcontrib>Toro‐Ramos, Tatiana</creatorcontrib><creatorcontrib>Widen, Elizabeth</creatorcontrib><creatorcontrib>Rosenn, Barak</creatorcontrib><creatorcontrib>Crane, Janet</creatorcontrib><creatorcontrib>Horowitz, Michelle</creatorcontrib><creatorcontrib>Lin, Susan</creatorcontrib><creatorcontrib>Gidwani, Sonia</creatorcontrib><creatorcontrib>Paley, Charles</creatorcontrib><creatorcontrib>Thornton, John C.</creatorcontrib><creatorcontrib>Pi‐Sunyer, F. Xavier</creatorcontrib><creatorcontrib>Gallagher, Dympna</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Obesity (Silver Spring, Md.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Janumala, Isaiah</au><au>Toro‐Ramos, Tatiana</au><au>Widen, Elizabeth</au><au>Rosenn, Barak</au><au>Crane, Janet</au><au>Horowitz, Michelle</au><au>Lin, Susan</au><au>Gidwani, Sonia</au><au>Paley, Charles</au><au>Thornton, John C.</au><au>Pi‐Sunyer, F. Xavier</au><au>Gallagher, Dympna</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased Visceral Adipose Tissue Without Weight Retention at 59 Weeks Postpartum</atitle><jtitle>Obesity (Silver Spring, Md.)</jtitle><addtitle>Obesity (Silver Spring)</addtitle><date>2020-03</date><risdate>2020</risdate><volume>28</volume><issue>3</issue><spage>552</spage><epage>562</epage><pages>552-562</pages><issn>1930-7381</issn><eissn>1930-739X</eissn><abstract>Objective
This study aimed to determine whether controlling maternal gestational weight gain (GWG) influences adipose tissue distribution at 1 year postpartum.
Methods
Women with overweight or obesity (n = 210, BMI ≥ 25 or ≥ 30) were randomized to a lifestyle intervention (LI) designed to control GWG or to usual obstetrical care (UC). Measures included anthropometry, whole‐body magnetic resonance imaging for visceral (VAT), intermuscular, and subcutaneous adipose tissue, and cardiometabolic risk factors in pregnancy (15 and 35 weeks) and after delivery (15 and 59 weeks).
Results
Baseline (15 weeks) characteristics were similar (mean [SD]: age, 33.8 [4.3] years; weight, 81.9 [13.7] kg; BMI, 30.4 [4.5]; gestational age at randomization, 14.9 [0.8] weeks). LI had less GWG (1.79 kg; P = 0.003) and subcutaneous adipose tissue gain at 35 weeks gestation (P < 0.01). UC postpartum weight (2.92 kg) was higher at 15 weeks but not different from baseline or LI at 59 weeks postpartum. Postpartum VAT increased from baseline in LI by 0.23 kg at 15 weeks and 0.55 kg at 59 weeks; in UC, it increased by 0.34 kg at 15 and 59 weeks. Intermuscular adipose tissue remained elevated in LI (0.22 kg) at 59 weeks. VAT was associated with several cardiometabolic risk factors at 59 weeks.
Conclusions
Despite no weight retention at 59 weeks postpartum, women had increased VAT by ~30%. Postpartum modifiable behaviors are warranted to lower the risk of VAT retention.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>32030911</pmid><doi>10.1002/oby.22736</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0003-1769-9754</orcidid><orcidid>https://orcid.org/0000-0002-9574-6109</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1930-7381 |
| ispartof | Obesity (Silver Spring, Md.), 2020-03, Vol.28 (3), p.552-562 |
| issn | 1930-7381 1930-739X |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7042094 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Wiley Free Content |
| subjects | Abdomen Adult Age Body composition Body fat Cholesterol Diabetes Exercise Female Humans Hypotheses Intervention Intra-Abdominal Fat - physiopathology Lifestyles Magnetic resonance imaging Obesity Physical fitness Postpartum Period Pregnancy Retention Tumor necrosis factor-TNF Variables Whole Body Imaging - methods Womens health |
| title | Increased Visceral Adipose Tissue Without Weight Retention at 59 Weeks Postpartum |
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