New HER2-negative breast cancer subtype responsive to anti-HER2 therapy identified

Purpose HER2 signaling functional activity may be important to measure in addition to HER2 protein quantification when identifying patients eligible for HER2 therapies. A HER2 Signaling Function (CELx HSF) Test for HER2-negative patients uses patient’s live tumor cells on a biosensor to identify pat...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2020-03, Vol.146 (3), p.605-619
Hauptverfasser:	MacNeil, Ian A., Burns, David J., Rich, Benjamin E., Soltani, Sajjad M., Kharbush, Samantha, Osterhaus, Nicole G., Sullivan, Brian F., Hawkins, Douglas M., Pietruska, Jodie R., Laing, Lance G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - pharmacology Biomarkers, Tumor - analysis Biosensors Breast cancer Breast Neoplasms - metabolism Cancer Research Electric Impedance ErbB-2 protein Female Hematology Humans Internal Medicine Medicine Medicine & Public Health Mice Oncology Original Article – Cancer Research Original – Cancer Research Patients Receptor, ErbB-2 - metabolism Signal Transduction - physiology Tumor cells Xenograft Model Antitumor Assays Xenografts
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