Histone methyltransferase Nsd2 is required for follicular helper T cell differentiation

Follicular helper T (Tfh) cells provide essential help for humoral immune response. Transcriptional factor Bcl6 is the master regulator for Tfh generation and is induced very early after T cell activation in a CD28-dependent manner, but how CD28 signal promotes Bcl6 early expression remains unknown....

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Veröffentlicht in:	The Journal of experimental medicine 2020-01, Vol.217 (1)
Hauptverfasser:	Long, Xuehui, Zhang, Le, Zhang, Yang, Min, Min, Lin, Bichun, Chen, Jingjing, Ma, Xiaojie, Zhai, Sulan, Cai, Zhenming, Liu, Yingxia, Lu, Yanlai, Che, Nan, Tan, Wenfeng, Qin, Jun, Wang, Xiaoming
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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