Retinal pigment epithelium polarity in health and blinding diseases

The polarized phenotype of the retinal pigment epithelium is crucial for the outer retina-blood barrier and support of photoreceptors and underlying choroid, and its disruption plays a central role in degenerative retinopathies. Although the mechanisms of polarization remain mostly unknown, they are...

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Veröffentlicht in:	Current opinion in cell biology 2020-02, Vol.62, p.37-45
Hauptverfasser:	Caceres, Paulo S, Rodriguez-Boulan, Enrique
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bruch Membrane - physiopathology Humans Retinal Pigment Epithelium - physiology
Online-Zugang:	Volltext
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