Some Gammaproteobacteria are enriched within CD14+ macrophages from intestinal lamina propria of Crohn’s disease patients versus mucus

Crohn’s disease causes chronic inflammation in the gastrointestinal tract and its pathogenesis remains unclear. In the intestine of Crohn’s disease patients, CD14 + CD11 + CD163 low macrophages contribute to inflammation through the induction of Th17 cells and production of inflammatory cytokines; t...

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Veröffentlicht in:	Scientific reports 2020-02, Vol.10 (1), p.2988-2988, Article 2988
Hauptverfasser:	Sekido, Yuki, Nishimura, Junichi, Nakano, Kazuhiro, Osu, Takeaki, Chow, Cheryl-Emiliane T., Matsuno, Hiroshi, Ogino, Takayuki, Fujino, Shiki, Miyoshi, Norikatsu, Takahashi, Hidekazu, Uemura, Mamoru, Matsuda, Chu, Kayama, Hisako, Mori, Masaki, Doki, Yuichiro, Takeda, Kiyoshi, Uchino, Motoi, Ikeuchi, Hiroki, Mizushima, Tsunekazu
Format:	Artikel
Sprache:	eng
Schlagworte:	13/31 38/22 45/23 45/77 631/208/325/1506 631/250/249/2510/1402 631/250/262 631/326/2565/2134 692/4020/1503/257/1402 Adult Aged Bacteria CD11c antigen CD14 antigen Crohn Disease - immunology Crohn Disease - microbiology Crohn Disease - pathology Crohn Disease - surgery Crohn's disease Cytokines DNA, Bacterial - isolation & purification Female Flow cytometry Gammaproteobacteria - genetics Gammaproteobacteria - immunology Gammaproteobacteria - isolation & purification Gastrointestinal tract Genetic testing Helper cells Hospitals Humanities and Social Sciences Humans Ileum - cytology Ileum - immunology Ileum - microbiology Ileum - pathology Immunology Inflammation Inflammatory bowel disease Interleukin 10 Intestinal Mucosa - cytology Intestinal Mucosa - immunology Intestinal Mucosa - microbiology Intestinal Mucosa - pathology Intestine Lamina propria Lipopolysaccharide Receptors - metabolism Lymphocytes T Macrophages Macrophages - immunology Macrophages - metabolism Macrophages - microbiology Male Medicine Microbiota Middle Aged Mucus multidisciplinary Pseudomonadaceae RNA, Ribosomal, 16S - genetics rRNA 16S Science Science (multidisciplinary) Statistical analysis Surgery Young Adult
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