Prenatal intermittent hypoxia sensitizes the laryngeal chemoreflex, blocks serotoninergic shortening of the reflex, and reduces 5-HT3 receptor binding in the NTS in anesthetized rat pups

We tested the hypothesis that exposure to intermittent hypoxia (IH) during pregnancy would prolong the laryngeal chemoreflex (LCR) and diminish the capacity of serotonin (5-hydroxytryptamine; 5-HT) to terminate the LCR. Prenatal exposure to IH was associated with significant prolongation of the LCR...

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Veröffentlicht in:	Experimental neurology 2020-04, Vol.326, p.113166-113166, Article 113166
Hauptverfasser:	Donnelly, William T., Haynes, Robin L., Commons, Kathryn G., Erickson, Drexel J., Panzini, Chris M., Xia, Luxi, Han, Q. Joyce, Leiter, J.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT3 receptor Autonomic neuroscience Autoradiography Intermittent hypoxia Laryngeal chemoreflex Serotonin SIDS
Online-Zugang:	Volltext
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