The Effect of Myocardial Surgical Revascularization on Left Ventricular Late Potentials
Background: The presence of ventricular late potentials (LP) is an important indicator for the development of ventricular tachyarrhythmias due to ischemic heart disease. The effect of myocardial revascularization on LP has remained controversial. The purpose of this study was to determine whether co...
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| Veröffentlicht in: | Annals of noninvasive electrocardiology 2001-04, Vol.6 (2), p.84-91 |
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| creator | Can, Levent Kayikçioǧlu, Meral Halil, Halil Kültürsay, Hakan Evrengül, Harun Kumanlioǧlu, Kamil Turkoglu, Cüneyt |
| description | Background: The presence of ventricular late potentials (LP) is an important indicator for the development of ventricular tachyarrhythmias due to ischemic heart disease. The effect of myocardial revascularization on LP has remained controversial. The purpose of this study was to determine whether complete myocardial surgical revascularization (CABG) documented by myocardial perfusion scintigraphy might alter the substrate responsible for LP.
Methods: Prospectively, enrolled patients undergoing elective CABG were evaluated with thallium‐201 myocardial perfusion scintigraphy and signal‐ averaged ECG pre‐ and postoperatively. SAECG recordings were obtained serially: before, 48–72 hours and 3 months after CABG. LPS were defined as positive if SAECG met at least two of Gomes criteria. Scintigraphies were performed pre‐and 3 months postoperatively for determination of the success of revascularization. Changes observed in SAECG recordings after CABG were compared between those with and without successful revascularization.
Results: CABG resulted in successful revascularization in 23 patients and was unsuccessful in 17 (no change or deterioration of the perfusion defects). Preoperative SAECG values were not different between groups except for RMS values. The incidence of LP decreased significantly postoperatively in patients with improved myocardial perfusion, whereas there were no changes in patients who did not have postoperative perfusion improvement (McNemar test, P < 0.05).
Conclusions: LPs disappear following the elimination of myocardial ischemia by complete surgical revascularization. Persistence of ischemia following CABG usually results in the persistence of late potentials. The incidence of ventricular arrhythmias is expected to be unchanged in these patients and they should be reevaluated for reinterventions. A.N.E. 2001;6(2):84–91 |
| doi_str_mv | 10.1111/j.1542-474X.2001.tb00091.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7027657</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>70816725</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5434-8c63199233dd0db8f587a2e79a4d6968c71fc3b5e1d4cae900d4361db1a5eb43</originalsourceid><addsrcrecordid>eNqVUV1v0zAUtRCIjcFfQBFIvCX4K3HCA9JWdQWpDMQqtjfL8cfmksbDdkbLr8ehUQePWJbule85517fA8ArBAuUztt1gUqKc8rodYEhREVsIYQNKraPwPGh9DjlsMY5w_D6CDwLYQ0hxhSzp-AIIUIIqugxuFrd6mxujJYxcyb7tHNSeGVFl10O_sbKlHzV9yLIoRPe_hLRuj5Ld6lNzL7pPnr7p5QtRdTZFxfTU2KH5-CJSUG_mOIJWJ3PV7MP-fLz4uPsdJnLkhKa17IiqGkwIUpB1damrJnAmjWCqqqpasmQkaQtNVJUCt1AqCipkGqRKHVLyQl4v5e9G9qNVnIcSHT8ztuN8DvuhOX_Vnp7y2_cPWcQs6pkSeDNJODdj0GHyDc2SN11otduCAlXo4rhMgHf7YHSuxC8NocmCPLRFr7m4-75uHs-2sInW_g2kV_-PeYDdfIhAV5PgLRq0RkvemnDAdc0BGH88NufttO7_xiAn17MZ_XYJt8L2BD19iAg_HdeMcJKfnWx4DUil-ezM8YX5DdOGbr_</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70816725</pqid></control><display><type>article</type><title>The Effect of Myocardial Surgical Revascularization on Left Ventricular Late Potentials</title><source>Wiley Online Library - AutoHoldings Journals</source><source>PubMed Central Free</source><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Can, Levent ; Kayikçioǧlu, Meral ; Halil, Halil ; Kültürsay, Hakan ; Evrengül, Harun ; Kumanlioǧlu, Kamil ; Turkoglu, Cüneyt</creator><creatorcontrib>Can, Levent ; Kayikçioǧlu, Meral ; Halil, Halil ; Kültürsay, Hakan ; Evrengül, Harun ; Kumanlioǧlu, Kamil ; Turkoglu, Cüneyt</creatorcontrib><description>Background: The presence of ventricular late potentials (LP) is an important indicator for the development of ventricular tachyarrhythmias due to ischemic heart disease. The effect of myocardial revascularization on LP has remained controversial. The purpose of this study was to determine whether complete myocardial surgical revascularization (CABG) documented by myocardial perfusion scintigraphy might alter the substrate responsible for LP.
Methods: Prospectively, enrolled patients undergoing elective CABG were evaluated with thallium‐201 myocardial perfusion scintigraphy and signal‐ averaged ECG pre‐ and postoperatively. SAECG recordings were obtained serially: before, 48–72 hours and 3 months after CABG. LPS were defined as positive if SAECG met at least two of Gomes criteria. Scintigraphies were performed pre‐and 3 months postoperatively for determination of the success of revascularization. Changes observed in SAECG recordings after CABG were compared between those with and without successful revascularization.
Results: CABG resulted in successful revascularization in 23 patients and was unsuccessful in 17 (no change or deterioration of the perfusion defects). Preoperative SAECG values were not different between groups except for RMS values. The incidence of LP decreased significantly postoperatively in patients with improved myocardial perfusion, whereas there were no changes in patients who did not have postoperative perfusion improvement (McNemar test, P < 0.05).
Conclusions: LPs disappear following the elimination of myocardial ischemia by complete surgical revascularization. Persistence of ischemia following CABG usually results in the persistence of late potentials. The incidence of ventricular arrhythmias is expected to be unchanged in these patients and they should be reevaluated for reinterventions. A.N.E. 2001;6(2):84–91</description><identifier>ISSN: 1082-720X</identifier><identifier>EISSN: 1542-474X</identifier><identifier>DOI: 10.1111/j.1542-474X.2001.tb00091.x</identifier><identifier>PMID: 11333164</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Action Potentials ; Adult ; Aged ; Analysis of Variance ; Biological and medical sciences ; Coronary Artery Bypass - methods ; coronary artery bypass grafting ; Coronary Disease - diagnostic imaging ; Coronary Disease - etiology ; Coronary Disease - physiopathology ; Coronary Disease - surgery ; Electrocardiography - standards ; Female ; Humans ; late potentials ; Male ; Medical sciences ; Middle Aged ; myocardial perfusion scintigraphy ; Predictive Value of Tests ; Prospective Studies ; Risk Factors ; Signal Processing, Computer-Assisted ; signal- averaged ECG ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the heart ; Thallium Radioisotopes ; Tomography, Emission-Computed, Single-Photon - standards ; Treatment Outcome ; Ventricular Function, Left</subject><ispartof>Annals of noninvasive electrocardiology, 2001-04, Vol.6 (2), p.84-91</ispartof><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5434-8c63199233dd0db8f587a2e79a4d6968c71fc3b5e1d4cae900d4361db1a5eb43</citedby><cites>FETCH-LOGICAL-c5434-8c63199233dd0db8f587a2e79a4d6968c71fc3b5e1d4cae900d4361db1a5eb43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027657/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027657/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,309,310,314,727,780,784,789,790,885,1417,23930,23931,25140,27924,27925,45574,45575,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=993122$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11333164$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Can, Levent</creatorcontrib><creatorcontrib>Kayikçioǧlu, Meral</creatorcontrib><creatorcontrib>Halil, Halil</creatorcontrib><creatorcontrib>Kültürsay, Hakan</creatorcontrib><creatorcontrib>Evrengül, Harun</creatorcontrib><creatorcontrib>Kumanlioǧlu, Kamil</creatorcontrib><creatorcontrib>Turkoglu, Cüneyt</creatorcontrib><title>The Effect of Myocardial Surgical Revascularization on Left Ventricular Late Potentials</title><title>Annals of noninvasive electrocardiology</title><addtitle>Ann Noninvasive Electrocardiol</addtitle><description>Background: The presence of ventricular late potentials (LP) is an important indicator for the development of ventricular tachyarrhythmias due to ischemic heart disease. The effect of myocardial revascularization on LP has remained controversial. The purpose of this study was to determine whether complete myocardial surgical revascularization (CABG) documented by myocardial perfusion scintigraphy might alter the substrate responsible for LP.
Methods: Prospectively, enrolled patients undergoing elective CABG were evaluated with thallium‐201 myocardial perfusion scintigraphy and signal‐ averaged ECG pre‐ and postoperatively. SAECG recordings were obtained serially: before, 48–72 hours and 3 months after CABG. LPS were defined as positive if SAECG met at least two of Gomes criteria. Scintigraphies were performed pre‐and 3 months postoperatively for determination of the success of revascularization. Changes observed in SAECG recordings after CABG were compared between those with and without successful revascularization.
Results: CABG resulted in successful revascularization in 23 patients and was unsuccessful in 17 (no change or deterioration of the perfusion defects). Preoperative SAECG values were not different between groups except for RMS values. The incidence of LP decreased significantly postoperatively in patients with improved myocardial perfusion, whereas there were no changes in patients who did not have postoperative perfusion improvement (McNemar test, P < 0.05).
Conclusions: LPs disappear following the elimination of myocardial ischemia by complete surgical revascularization. Persistence of ischemia following CABG usually results in the persistence of late potentials. The incidence of ventricular arrhythmias is expected to be unchanged in these patients and they should be reevaluated for reinterventions. A.N.E. 2001;6(2):84–91</description><subject>Action Potentials</subject><subject>Adult</subject><subject>Aged</subject><subject>Analysis of Variance</subject><subject>Biological and medical sciences</subject><subject>Coronary Artery Bypass - methods</subject><subject>coronary artery bypass grafting</subject><subject>Coronary Disease - diagnostic imaging</subject><subject>Coronary Disease - etiology</subject><subject>Coronary Disease - physiopathology</subject><subject>Coronary Disease - surgery</subject><subject>Electrocardiography - standards</subject><subject>Female</subject><subject>Humans</subject><subject>late potentials</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>myocardial perfusion scintigraphy</subject><subject>Predictive Value of Tests</subject><subject>Prospective Studies</subject><subject>Risk Factors</subject><subject>Signal Processing, Computer-Assisted</subject><subject>signal- averaged ECG</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the heart</subject><subject>Thallium Radioisotopes</subject><subject>Tomography, Emission-Computed, Single-Photon - standards</subject><subject>Treatment Outcome</subject><subject>Ventricular Function, Left</subject><issn>1082-720X</issn><issn>1542-474X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVUV1v0zAUtRCIjcFfQBFIvCX4K3HCA9JWdQWpDMQqtjfL8cfmksbDdkbLr8ehUQePWJbule85517fA8ArBAuUztt1gUqKc8rodYEhREVsIYQNKraPwPGh9DjlsMY5w_D6CDwLYQ0hxhSzp-AIIUIIqugxuFrd6mxujJYxcyb7tHNSeGVFl10O_sbKlHzV9yLIoRPe_hLRuj5Ld6lNzL7pPnr7p5QtRdTZFxfTU2KH5-CJSUG_mOIJWJ3PV7MP-fLz4uPsdJnLkhKa17IiqGkwIUpB1damrJnAmjWCqqqpasmQkaQtNVJUCt1AqCipkGqRKHVLyQl4v5e9G9qNVnIcSHT8ztuN8DvuhOX_Vnp7y2_cPWcQs6pkSeDNJODdj0GHyDc2SN11otduCAlXo4rhMgHf7YHSuxC8NocmCPLRFr7m4-75uHs-2sInW_g2kV_-PeYDdfIhAV5PgLRq0RkvemnDAdc0BGH88NufttO7_xiAn17MZ_XYJt8L2BD19iAg_HdeMcJKfnWx4DUil-ezM8YX5DdOGbr_</recordid><startdate>200104</startdate><enddate>200104</enddate><creator>Can, Levent</creator><creator>Kayikçioǧlu, Meral</creator><creator>Halil, Halil</creator><creator>Kültürsay, Hakan</creator><creator>Evrengül, Harun</creator><creator>Kumanlioǧlu, Kamil</creator><creator>Turkoglu, Cüneyt</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>200104</creationdate><title>The Effect of Myocardial Surgical Revascularization on Left Ventricular Late Potentials</title><author>Can, Levent ; Kayikçioǧlu, Meral ; Halil, Halil ; Kültürsay, Hakan ; Evrengül, Harun ; Kumanlioǧlu, Kamil ; Turkoglu, Cüneyt</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5434-8c63199233dd0db8f587a2e79a4d6968c71fc3b5e1d4cae900d4361db1a5eb43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Action Potentials</topic><topic>Adult</topic><topic>Aged</topic><topic>Analysis of Variance</topic><topic>Biological and medical sciences</topic><topic>Coronary Artery Bypass - methods</topic><topic>coronary artery bypass grafting</topic><topic>Coronary Disease - diagnostic imaging</topic><topic>Coronary Disease - etiology</topic><topic>Coronary Disease - physiopathology</topic><topic>Coronary Disease - surgery</topic><topic>Electrocardiography - standards</topic><topic>Female</topic><topic>Humans</topic><topic>late potentials</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>myocardial perfusion scintigraphy</topic><topic>Predictive Value of Tests</topic><topic>Prospective Studies</topic><topic>Risk Factors</topic><topic>Signal Processing, Computer-Assisted</topic><topic>signal- averaged ECG</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the heart</topic><topic>Thallium Radioisotopes</topic><topic>Tomography, Emission-Computed, Single-Photon - standards</topic><topic>Treatment Outcome</topic><topic>Ventricular Function, Left</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Can, Levent</creatorcontrib><creatorcontrib>Kayikçioǧlu, Meral</creatorcontrib><creatorcontrib>Halil, Halil</creatorcontrib><creatorcontrib>Kültürsay, Hakan</creatorcontrib><creatorcontrib>Evrengül, Harun</creatorcontrib><creatorcontrib>Kumanlioǧlu, Kamil</creatorcontrib><creatorcontrib>Turkoglu, Cüneyt</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of noninvasive electrocardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Can, Levent</au><au>Kayikçioǧlu, Meral</au><au>Halil, Halil</au><au>Kültürsay, Hakan</au><au>Evrengül, Harun</au><au>Kumanlioǧlu, Kamil</au><au>Turkoglu, Cüneyt</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effect of Myocardial Surgical Revascularization on Left Ventricular Late Potentials</atitle><jtitle>Annals of noninvasive electrocardiology</jtitle><addtitle>Ann Noninvasive Electrocardiol</addtitle><date>2001-04</date><risdate>2001</risdate><volume>6</volume><issue>2</issue><spage>84</spage><epage>91</epage><pages>84-91</pages><issn>1082-720X</issn><eissn>1542-474X</eissn><abstract>Background: The presence of ventricular late potentials (LP) is an important indicator for the development of ventricular tachyarrhythmias due to ischemic heart disease. The effect of myocardial revascularization on LP has remained controversial. The purpose of this study was to determine whether complete myocardial surgical revascularization (CABG) documented by myocardial perfusion scintigraphy might alter the substrate responsible for LP.
Methods: Prospectively, enrolled patients undergoing elective CABG were evaluated with thallium‐201 myocardial perfusion scintigraphy and signal‐ averaged ECG pre‐ and postoperatively. SAECG recordings were obtained serially: before, 48–72 hours and 3 months after CABG. LPS were defined as positive if SAECG met at least two of Gomes criteria. Scintigraphies were performed pre‐and 3 months postoperatively for determination of the success of revascularization. Changes observed in SAECG recordings after CABG were compared between those with and without successful revascularization.
Results: CABG resulted in successful revascularization in 23 patients and was unsuccessful in 17 (no change or deterioration of the perfusion defects). Preoperative SAECG values were not different between groups except for RMS values. The incidence of LP decreased significantly postoperatively in patients with improved myocardial perfusion, whereas there were no changes in patients who did not have postoperative perfusion improvement (McNemar test, P < 0.05).
Conclusions: LPs disappear following the elimination of myocardial ischemia by complete surgical revascularization. Persistence of ischemia following CABG usually results in the persistence of late potentials. The incidence of ventricular arrhythmias is expected to be unchanged in these patients and they should be reevaluated for reinterventions. A.N.E. 2001;6(2):84–91</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>11333164</pmid><doi>10.1111/j.1542-474X.2001.tb00091.x</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Action Potentials Adult Aged Analysis of Variance Biological and medical sciences Coronary Artery Bypass - methods coronary artery bypass grafting Coronary Disease - diagnostic imaging Coronary Disease - etiology Coronary Disease - physiopathology Coronary Disease - surgery Electrocardiography - standards Female Humans late potentials Male Medical sciences Middle Aged myocardial perfusion scintigraphy Predictive Value of Tests Prospective Studies Risk Factors Signal Processing, Computer-Assisted signal- averaged ECG Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Thallium Radioisotopes Tomography, Emission-Computed, Single-Photon - standards Treatment Outcome Ventricular Function, Left |
| title | The Effect of Myocardial Surgical Revascularization on Left Ventricular Late Potentials |
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