Observer uncertainties of soft tissue‐based patient positioning in IGRT
Purpose There remain uncertainties due to inter‐ and intraobserver variability in soft‐tissue‐based patient positioning even with the use of image‐guided radiation therapy (IGRT). This study aimed to reveal observer uncertainties of soft‐tissue‐based patient positioning on cone‐beam computed tomogra...
Gespeichert in:
| Veröffentlicht in: | Journal of applied clinical medical physics 2020-02, Vol.21 (2), p.73-81 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 81 |
|---|---|
| container_issue | 2 |
| container_start_page | 73 |
| container_title | Journal of applied clinical medical physics |
| container_volume | 21 |
| creator | Hirose, Taka‐aki Arimura, Hidetaka Fukunaga, Jun‐ichi Ohga, Saiji Yoshitake, Tadamasa Shioyama, Yoshiyuki |
| description | Purpose
There remain uncertainties due to inter‐ and intraobserver variability in soft‐tissue‐based patient positioning even with the use of image‐guided radiation therapy (IGRT). This study aimed to reveal observer uncertainties of soft‐tissue‐based patient positioning on cone‐beam computed tomography (CBCT) images for prostate cancer IGRT.
Methods
Twenty‐six patients (7–8 fractions/patient, total number of 204 fractions) who underwent IGRT for prostate cancer were selected. Six radiation therapists retrospectively measured prostate cancer location errors (PCLEs) of soft‐tissue‐based patient positioning between planning CT (pCT) and pretreatment CBCT (pre‐CBCT) images after automatic bone‐based registration. Observer uncertainties were evaluated based on residual errors, which denoted the differences between soft‐tissue and reference positioning errors. Reference positioning errors were obtained as PCLEs of contour‐based patient positioning between pCT and pre‐CBCT images. Intraobserver variations were obtained from the difference between the first and second soft‐tissue‐based patient positioning repeated by the same observer for each fraction. Systematic and random errors of inter‐ and intraobserver variations were calculated in anterior–posterior (AP), superior–inferior (SI), and left–right (LR) directions. Finally, clinical target volume (CTV)‐to‐planning target volume (PTV) margins were obtained from systematic and random errors of inter‐ and intraobserver variations in AP, SI, and LR directions.
Results
Interobserver variations in AP, SI, and LR directions were 0.9, 0.9, and 0.5 mm, respectively, for the systematic error, and 1.8, 2.2, and 1.1 mm, respectively, for random error. Intraobserver variations were |
| doi_str_mv | 10.1002/acm2.12817 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7021001</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2354742536</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5427-887afb45513e4732155191df95a6ea0627d27f49fac6daab3ab9fe5721f588033</originalsourceid><addsrcrecordid>eNp9kctKAzEUhoMo1tvGB5ABNyK05jqZbAQpWguKILoOmZmkRqZJTWaU7nwEn9EnMbVV1IWrHDgfH3_OD8A-ggMEIT5R1RQPEC4QXwNbiOG8LwSi6z_mHtiO8RFChApSbIIeQYJxkdMtML4pow7POmSdq3RolXWt1THzJovetFlrY-z0--tbqaKus5lKW9dmMx9ta72zbpJZl41Ht3e7YMOoJuq91bsD7i_O74aX_aub0Xh4dtWvGMW8XxRcmZIyhoimnGCUJoFqI5jKtYI55jXmhgqjqrxWqiSqFEYzjpFhRQEJ2QGnS--sK6e6rlKcoBo5C3aqwlx6ZeXvjbMPcuKfJYc4nQslwdFKEPxTp2MrpzZWummU076LEhOKCaMCioQe_kEffRdc-p5cIJxiRvJEHS-pKvgYgzbfYRCUi4bkoiH52VCCD37G_0a_KkkAWgIvttHzf1TybHiNl9IPMaKb8Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2354742536</pqid></control><display><type>article</type><title>Observer uncertainties of soft tissue‐based patient positioning in IGRT</title><source>MEDLINE</source><source>Wiley Online Library Open Access</source><source>DOAJ Directory of Open Access Journals</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Hirose, Taka‐aki ; Arimura, Hidetaka ; Fukunaga, Jun‐ichi ; Ohga, Saiji ; Yoshitake, Tadamasa ; Shioyama, Yoshiyuki</creator><creatorcontrib>Hirose, Taka‐aki ; Arimura, Hidetaka ; Fukunaga, Jun‐ichi ; Ohga, Saiji ; Yoshitake, Tadamasa ; Shioyama, Yoshiyuki</creatorcontrib><description>Purpose
There remain uncertainties due to inter‐ and intraobserver variability in soft‐tissue‐based patient positioning even with the use of image‐guided radiation therapy (IGRT). This study aimed to reveal observer uncertainties of soft‐tissue‐based patient positioning on cone‐beam computed tomography (CBCT) images for prostate cancer IGRT.
Methods
Twenty‐six patients (7–8 fractions/patient, total number of 204 fractions) who underwent IGRT for prostate cancer were selected. Six radiation therapists retrospectively measured prostate cancer location errors (PCLEs) of soft‐tissue‐based patient positioning between planning CT (pCT) and pretreatment CBCT (pre‐CBCT) images after automatic bone‐based registration. Observer uncertainties were evaluated based on residual errors, which denoted the differences between soft‐tissue and reference positioning errors. Reference positioning errors were obtained as PCLEs of contour‐based patient positioning between pCT and pre‐CBCT images. Intraobserver variations were obtained from the difference between the first and second soft‐tissue‐based patient positioning repeated by the same observer for each fraction. Systematic and random errors of inter‐ and intraobserver variations were calculated in anterior–posterior (AP), superior–inferior (SI), and left–right (LR) directions. Finally, clinical target volume (CTV)‐to‐planning target volume (PTV) margins were obtained from systematic and random errors of inter‐ and intraobserver variations in AP, SI, and LR directions.
Results
Interobserver variations in AP, SI, and LR directions were 0.9, 0.9, and 0.5 mm, respectively, for the systematic error, and 1.8, 2.2, and 1.1 mm, respectively, for random error. Intraobserver variations were <0.2 mm in all directions. CTV‐to‐PTV margins in AP, SI, and LR directions were 3.5, 3.8, and 2.1 mm, respectively.
Conclusion
Intraobserver variability was sufficiently small and would be negligible. However, uncertainties due to interobserver variability for soft‐tissue‐based patient positioning using CBCT images should be considered in CTV‐to‐PTV margins.</description><identifier>ISSN: 1526-9914</identifier><identifier>EISSN: 1526-9914</identifier><identifier>DOI: 10.1002/acm2.12817</identifier><identifier>PMID: 31957964</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>Aged ; Aged, 80 and over ; Antigens ; Cancer therapies ; Cone-Beam Computed Tomography ; Humans ; interobserver variation ; intraobserver variation ; Male ; Middle Aged ; Models, Statistical ; Observer Variation ; Patient Positioning ; Prostate cancer ; prostate cancer image‐guided radiation therapy ; Prostatic Neoplasms - diagnostic imaging ; PTV margin ; Radiation Oncology Physics ; Radiation therapy ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted ; Radiotherapy, Image-Guided - methods ; Radiotherapy, Intensity-Modulated - methods ; Registration ; Reproducibility of Results ; Retrospective Studies ; soft‐tissue‐based patient positioning ; Studies ; Tomography ; Tomography, X-Ray Computed ; Uncertainty</subject><ispartof>Journal of applied clinical medical physics, 2020-02, Vol.21 (2), p.73-81</ispartof><rights>2020 The Authors. published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.</rights><rights>2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.</rights><rights>2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5427-887afb45513e4732155191df95a6ea0627d27f49fac6daab3ab9fe5721f588033</citedby><cites>FETCH-LOGICAL-c5427-887afb45513e4732155191df95a6ea0627d27f49fac6daab3ab9fe5721f588033</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021001/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021001/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,1411,11541,27901,27902,45550,45551,46027,46451,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31957964$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hirose, Taka‐aki</creatorcontrib><creatorcontrib>Arimura, Hidetaka</creatorcontrib><creatorcontrib>Fukunaga, Jun‐ichi</creatorcontrib><creatorcontrib>Ohga, Saiji</creatorcontrib><creatorcontrib>Yoshitake, Tadamasa</creatorcontrib><creatorcontrib>Shioyama, Yoshiyuki</creatorcontrib><title>Observer uncertainties of soft tissue‐based patient positioning in IGRT</title><title>Journal of applied clinical medical physics</title><addtitle>J Appl Clin Med Phys</addtitle><description>Purpose
There remain uncertainties due to inter‐ and intraobserver variability in soft‐tissue‐based patient positioning even with the use of image‐guided radiation therapy (IGRT). This study aimed to reveal observer uncertainties of soft‐tissue‐based patient positioning on cone‐beam computed tomography (CBCT) images for prostate cancer IGRT.
Methods
Twenty‐six patients (7–8 fractions/patient, total number of 204 fractions) who underwent IGRT for prostate cancer were selected. Six radiation therapists retrospectively measured prostate cancer location errors (PCLEs) of soft‐tissue‐based patient positioning between planning CT (pCT) and pretreatment CBCT (pre‐CBCT) images after automatic bone‐based registration. Observer uncertainties were evaluated based on residual errors, which denoted the differences between soft‐tissue and reference positioning errors. Reference positioning errors were obtained as PCLEs of contour‐based patient positioning between pCT and pre‐CBCT images. Intraobserver variations were obtained from the difference between the first and second soft‐tissue‐based patient positioning repeated by the same observer for each fraction. Systematic and random errors of inter‐ and intraobserver variations were calculated in anterior–posterior (AP), superior–inferior (SI), and left–right (LR) directions. Finally, clinical target volume (CTV)‐to‐planning target volume (PTV) margins were obtained from systematic and random errors of inter‐ and intraobserver variations in AP, SI, and LR directions.
Results
Interobserver variations in AP, SI, and LR directions were 0.9, 0.9, and 0.5 mm, respectively, for the systematic error, and 1.8, 2.2, and 1.1 mm, respectively, for random error. Intraobserver variations were <0.2 mm in all directions. CTV‐to‐PTV margins in AP, SI, and LR directions were 3.5, 3.8, and 2.1 mm, respectively.
Conclusion
Intraobserver variability was sufficiently small and would be negligible. However, uncertainties due to interobserver variability for soft‐tissue‐based patient positioning using CBCT images should be considered in CTV‐to‐PTV margins.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antigens</subject><subject>Cancer therapies</subject><subject>Cone-Beam Computed Tomography</subject><subject>Humans</subject><subject>interobserver variation</subject><subject>intraobserver variation</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Models, Statistical</subject><subject>Observer Variation</subject><subject>Patient Positioning</subject><subject>Prostate cancer</subject><subject>prostate cancer image‐guided radiation therapy</subject><subject>Prostatic Neoplasms - diagnostic imaging</subject><subject>PTV margin</subject><subject>Radiation Oncology Physics</subject><subject>Radiation therapy</subject><subject>Radiotherapy Dosage</subject><subject>Radiotherapy Planning, Computer-Assisted</subject><subject>Radiotherapy, Image-Guided - methods</subject><subject>Radiotherapy, Intensity-Modulated - methods</subject><subject>Registration</subject><subject>Reproducibility of Results</subject><subject>Retrospective Studies</subject><subject>soft‐tissue‐based patient positioning</subject><subject>Studies</subject><subject>Tomography</subject><subject>Tomography, X-Ray Computed</subject><subject>Uncertainty</subject><issn>1526-9914</issn><issn>1526-9914</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kctKAzEUhoMo1tvGB5ABNyK05jqZbAQpWguKILoOmZmkRqZJTWaU7nwEn9EnMbVV1IWrHDgfH3_OD8A-ggMEIT5R1RQPEC4QXwNbiOG8LwSi6z_mHtiO8RFChApSbIIeQYJxkdMtML4pow7POmSdq3RolXWt1THzJovetFlrY-z0--tbqaKus5lKW9dmMx9ta72zbpJZl41Ht3e7YMOoJuq91bsD7i_O74aX_aub0Xh4dtWvGMW8XxRcmZIyhoimnGCUJoFqI5jKtYI55jXmhgqjqrxWqiSqFEYzjpFhRQEJ2QGnS--sK6e6rlKcoBo5C3aqwlx6ZeXvjbMPcuKfJYc4nQslwdFKEPxTp2MrpzZWummU076LEhOKCaMCioQe_kEffRdc-p5cIJxiRvJEHS-pKvgYgzbfYRCUi4bkoiH52VCCD37G_0a_KkkAWgIvttHzf1TybHiNl9IPMaKb8Q</recordid><startdate>202002</startdate><enddate>202002</enddate><creator>Hirose, Taka‐aki</creator><creator>Arimura, Hidetaka</creator><creator>Fukunaga, Jun‐ichi</creator><creator>Ohga, Saiji</creator><creator>Yoshitake, Tadamasa</creator><creator>Shioyama, Yoshiyuki</creator><general>John Wiley & Sons, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88I</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M2P</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PKEHL</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>202002</creationdate><title>Observer uncertainties of soft tissue‐based patient positioning in IGRT</title><author>Hirose, Taka‐aki ; Arimura, Hidetaka ; Fukunaga, Jun‐ichi ; Ohga, Saiji ; Yoshitake, Tadamasa ; Shioyama, Yoshiyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5427-887afb45513e4732155191df95a6ea0627d27f49fac6daab3ab9fe5721f588033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antigens</topic><topic>Cancer therapies</topic><topic>Cone-Beam Computed Tomography</topic><topic>Humans</topic><topic>interobserver variation</topic><topic>intraobserver variation</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Models, Statistical</topic><topic>Observer Variation</topic><topic>Patient Positioning</topic><topic>Prostate cancer</topic><topic>prostate cancer image‐guided radiation therapy</topic><topic>Prostatic Neoplasms - diagnostic imaging</topic><topic>PTV margin</topic><topic>Radiation Oncology Physics</topic><topic>Radiation therapy</topic><topic>Radiotherapy Dosage</topic><topic>Radiotherapy Planning, Computer-Assisted</topic><topic>Radiotherapy, Image-Guided - methods</topic><topic>Radiotherapy, Intensity-Modulated - methods</topic><topic>Registration</topic><topic>Reproducibility of Results</topic><topic>Retrospective Studies</topic><topic>soft‐tissue‐based patient positioning</topic><topic>Studies</topic><topic>Tomography</topic><topic>Tomography, X-Ray Computed</topic><topic>Uncertainty</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hirose, Taka‐aki</creatorcontrib><creatorcontrib>Arimura, Hidetaka</creatorcontrib><creatorcontrib>Fukunaga, Jun‐ichi</creatorcontrib><creatorcontrib>Ohga, Saiji</creatorcontrib><creatorcontrib>Yoshitake, Tadamasa</creatorcontrib><creatorcontrib>Shioyama, Yoshiyuki</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Science Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Science Database</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of applied clinical medical physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hirose, Taka‐aki</au><au>Arimura, Hidetaka</au><au>Fukunaga, Jun‐ichi</au><au>Ohga, Saiji</au><au>Yoshitake, Tadamasa</au><au>Shioyama, Yoshiyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Observer uncertainties of soft tissue‐based patient positioning in IGRT</atitle><jtitle>Journal of applied clinical medical physics</jtitle><addtitle>J Appl Clin Med Phys</addtitle><date>2020-02</date><risdate>2020</risdate><volume>21</volume><issue>2</issue><spage>73</spage><epage>81</epage><pages>73-81</pages><issn>1526-9914</issn><eissn>1526-9914</eissn><abstract>Purpose
There remain uncertainties due to inter‐ and intraobserver variability in soft‐tissue‐based patient positioning even with the use of image‐guided radiation therapy (IGRT). This study aimed to reveal observer uncertainties of soft‐tissue‐based patient positioning on cone‐beam computed tomography (CBCT) images for prostate cancer IGRT.
Methods
Twenty‐six patients (7–8 fractions/patient, total number of 204 fractions) who underwent IGRT for prostate cancer were selected. Six radiation therapists retrospectively measured prostate cancer location errors (PCLEs) of soft‐tissue‐based patient positioning between planning CT (pCT) and pretreatment CBCT (pre‐CBCT) images after automatic bone‐based registration. Observer uncertainties were evaluated based on residual errors, which denoted the differences between soft‐tissue and reference positioning errors. Reference positioning errors were obtained as PCLEs of contour‐based patient positioning between pCT and pre‐CBCT images. Intraobserver variations were obtained from the difference between the first and second soft‐tissue‐based patient positioning repeated by the same observer for each fraction. Systematic and random errors of inter‐ and intraobserver variations were calculated in anterior–posterior (AP), superior–inferior (SI), and left–right (LR) directions. Finally, clinical target volume (CTV)‐to‐planning target volume (PTV) margins were obtained from systematic and random errors of inter‐ and intraobserver variations in AP, SI, and LR directions.
Results
Interobserver variations in AP, SI, and LR directions were 0.9, 0.9, and 0.5 mm, respectively, for the systematic error, and 1.8, 2.2, and 1.1 mm, respectively, for random error. Intraobserver variations were <0.2 mm in all directions. CTV‐to‐PTV margins in AP, SI, and LR directions were 3.5, 3.8, and 2.1 mm, respectively.
Conclusion
Intraobserver variability was sufficiently small and would be negligible. However, uncertainties due to interobserver variability for soft‐tissue‐based patient positioning using CBCT images should be considered in CTV‐to‐PTV margins.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>31957964</pmid><doi>10.1002/acm2.12817</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1526-9914 |
| ispartof | Journal of applied clinical medical physics, 2020-02, Vol.21 (2), p.73-81 |
| issn | 1526-9914 1526-9914 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7021001 |
| source | MEDLINE; Wiley Online Library Open Access; DOAJ Directory of Open Access Journals; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Aged Aged, 80 and over Antigens Cancer therapies Cone-Beam Computed Tomography Humans interobserver variation intraobserver variation Male Middle Aged Models, Statistical Observer Variation Patient Positioning Prostate cancer prostate cancer image‐guided radiation therapy Prostatic Neoplasms - diagnostic imaging PTV margin Radiation Oncology Physics Radiation therapy Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted Radiotherapy, Image-Guided - methods Radiotherapy, Intensity-Modulated - methods Registration Reproducibility of Results Retrospective Studies soft‐tissue‐based patient positioning Studies Tomography Tomography, X-Ray Computed Uncertainty |
| title | Observer uncertainties of soft tissue‐based patient positioning in IGRT |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-16T11%3A34%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Observer%20uncertainties%20of%20soft%20tissue%E2%80%90based%20patient%20positioning%20in%20IGRT&rft.jtitle=Journal%20of%20applied%20clinical%20medical%20physics&rft.au=Hirose,%20Taka%E2%80%90aki&rft.date=2020-02&rft.volume=21&rft.issue=2&rft.spage=73&rft.epage=81&rft.pages=73-81&rft.issn=1526-9914&rft.eissn=1526-9914&rft_id=info:doi/10.1002/acm2.12817&rft_dat=%3Cproquest_pubme%3E2354742536%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2354742536&rft_id=info:pmid/31957964&rfr_iscdi=true |