Isatins Inhibit N5‑CAIR Synthetase by a Substrate Depletion Mechanism

The continued rise of antibiotic-resistant infections coupled with the limited pipeline of new antimicrobials highlights the pressing need for the development of new antibacterial agents. One potential pathway for new agents is de novo purine biosynthesis as studies have shown that bacteria and lowe...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemistry (Easton) 2019-04, Vol.58 (17), p.2260-2268
Hauptverfasser:	Streeter, Cale C, Lin, Qian, Firestine, Steven M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!