Energy Metabolism in Cancer: The Roles of STAT3 and STAT5 in the Regulation of Metabolism-Related Genes

A central characteristic of many types of cancer is altered energy metabolism processes such as enhanced glucose uptake and glycolysis and decreased oxidative metabolism. The regulation of energy metabolism is an elaborate process involving regulatory proteins such as HIF (pro-metastatic protein), w...

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Veröffentlicht in:	Cancers 2020-01, Vol.12 (1), p.124
Hauptverfasser:	Valle-Mendiola, Arturo, Soto-Cruz, Isabel
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Cancer Cell cycle Cell survival Cytokines Dehydrogenases Energy Energy metabolism Enzymes Fatty acids Gene expression Gene regulation Glucose Glycolysis Hypoxia Hypoxia-inducible factors Metabolic pathways Metabolism Metabolites Metastases Microenvironments Mitochondria Oxidation Oxidative metabolism Oxidative phosphorylation Phosphorylation Protein turnover Proteins Regulatory proteins Respiration Review Signal transduction Stat3 protein Stat5 protein Transcription activation Tumor microenvironment Tumors
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