Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy

Histone deacetylation inhibitors (HDACi) offer high potential for future cancer therapy as they can re-establish the expression of epigenetically silenced cell death programs. HDACi-induced autophagy offers the possibility to counteract the frequently present apoptosis-resistance as well as stress c...

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Veröffentlicht in:	Cancers 2019-12, Vol.12 (1), p.109
Hauptverfasser:	Mrakovcic, Maria, Fröhlich, Leopold F
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Autophagy Binding sites Cancer Cancer therapies Cell death Cytoplasm Deacetylation Developmental stages Genes Histone deacetylase Histones Homeostasis Kinases MicroRNAs Necrosis Oxidative stress Phagocytosis Physiology Proteins Review Tumorigenesis
Online-Zugang:	Volltext
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