Novel liver fibrosis model in Macaca fascicularis induced by thioacetamide

Although transplantation is the only definitive treatment for liver cirrhosis, there remains a shortage of donors, necessitating that novel treatments be developed. We aimed to establish a liver fibrosis model in Macaca fascicularis that can help accelerate preclinical research. Liver fibrosis was i...

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Veröffentlicht in:	Scientific reports 2020-02, Vol.10 (1), p.2450, Article 2450
Hauptverfasser:	Matsuo, Megumi, Murata, Soichiro, Hasegawa, Shunsuke, Hatada, Yumi, Ohtsuka, Masayuki, Taniguchi, Hideki
Format:	Artikel
Sprache:	eng
Schlagworte:	13/51 14/63 692/4020/4021 692/420/256 Animals Bile Carbon tetrachloride Cirrhosis Disease Models, Animal Disease Progression Fibrosis Histology Humanities and Social Sciences Liver Liver - drug effects Liver - pathology Liver - physiopathology Liver cirrhosis Liver Cirrhosis - chemically induced Liver Cirrhosis - pathology Liver Cirrhosis - physiopathology Liver Function Tests Macaca fascicularis Macaca fascicularis - physiology Mimicry multidisciplinary Science Science (multidisciplinary) Thioacetamide Transplantation
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