Isoprenaline protects intestinal stem cells from chemotherapy‐induced damage

Background and Purpose Damage to intestinal epithelial cells and mucosa limits the effectiveness of several anti‐cancer chemotherapeutic agents but the underlying mechanism (s) remain unknown. Little is known of how enteric nervous system regulates proliferation, differentiation, impairment, and reg...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of pharmacology 2020-02, Vol.177 (3), p.687-700
Hauptverfasser:	Zeng, Huihong, Li, Huan, Yue, Mengzhen, Fan, Ying, Cheng, Jiaoqi, Wu, Xincheng, Xu, Rui, Yang, Wuping, Li, Manjun, Tang, Jiahui, Chen, Hongping, Kuang, Bohai, Fan, Guangqin, Zhu, Qingxian, Shao, Lijian
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase 5-Fluorouracil AKT protein Animals Antineoplastic Agents - toxicity Apoptosis Cell cycle Cell proliferation Chemotherapy Cisplatin Enteric nervous system Epithelial cells Intestinal Mucosa Intestine Isoproterenol - pharmacology Male Mice Mice, Inbred C57BL Mucosa Parasympathetic nervous system Phosphatidylinositol 3-Kinases Regeneration Research Paper Research Papers Signal transduction Stem cell transplantation Stem Cells Sympathetic nerves
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!