Enterococcus faecalis α1–2‐mannosidase (EfMan‐I): an efficient catalyst for glycoprotein N‐glycan modification

While multiple α 1–2‐mannosidases are necessary for glycoprotein N‐glycan maturation in vertebrates, a single bacterial α1–2‐mannosidase can be sufficient to cleave all α1–2‐linked mannose residues in host glycoprotein N‐glycans. We report here the characterization and crystal structure of a new α1–...

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