Expression and function of umami receptors T1R1/T1R3 in gastric smooth muscle

Background l‐amino acids, such as monosodium glutamate (MSG), activate the umami receptor T1R1/T1R3. We previously showed increased peristalsis in response to activation of T1R1/T1R3 by MSG in mouse colon. However, the expression and function of these receptors in the different regions of the stomac...

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Veröffentlicht in:	Neurogastroenterology and motility 2020-02, Vol.32 (2), p.e13737-n/a
Hauptverfasser:	Crowe, Molly S., Wang, Hongxia, Blakeney, Bryan A., Mahavadi, Sunila, Singh, Kulpreet, Murthy, Karnam S., Grider, John R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Allosteric properties Animals Calcium Calcium (intracellular) cellular signalling Colon Female gastric motility Inosine monophosphate Male Mice Mice, Inbred C57BL Monosodium glutamate Muscle contraction Muscle, Smooth - metabolism Nitric oxide Nitric-oxide synthase Peristalsis Pertussis Pertussis toxin Receptor mechanisms Receptors, G-Protein-Coupled - metabolism Smooth muscle Stomach taste receptors Tetrodotoxin Umami
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