Holographic molecular binding assays

We demonstrate that holographic particle characterization can directly detect binding of proteins to functionalized colloidal probe particles by monitoring the associated change in the particles’ size. This label-free molecular binding assay uses in-line holographic video microscopy to measure the d...

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Veröffentlicht in:	Scientific reports 2020-02, Vol.10 (1), p.1932-1932, Article 1932
Hauptverfasser:	Zagzag, Yvonne, Soddu, M. Francesca, Hollingsworth, Andrew D., Grier, David G.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/61/32 639/624/1107 Humanities and Social Sciences Immunoglobulin G Immunoglobulins Measurement techniques Microfluidics Microscopy multidisciplinary Physics Population Proteins Science Science (multidisciplinary) Spheres
Online-Zugang:	Volltext
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