A 124-plex Microhaplotype Panel Based on Next-generation Sequencing Developed for Forensic Applications

Microhaplotypes are an emerging type of forensic genetic marker that are expected to support multiple forensic applications. Here, we developed a 124-plex panel for microhaplotype genotyping based on next-generation sequencing (NGS). The panel yielded intralocus and interlocus balanced sequencing da...

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Veröffentlicht in:	Scientific reports 2020-02, Vol.10 (1), p.1945-1945, Article 1945
Hauptverfasser:	Pang, Jing-Bo, Rao, Min, Chen, Qing-Feng, Ji, An-Quan, Zhang, Chi, Kang, Ke-Lai, Wu, Hao, Ye, Jian, Nie, Sheng-Jie, Wang, Le
Format:	Artikel
Sprache:	eng
Schlagworte:	45/23 45/29 631/1647/514/2254 692/4017 Alleles Asian People - genetics Capillary electrophoresis Deoxyribonucleic acid DNA DNA - genetics DNA Fingerprinting - methods Forensic Genetics Forensic science Forensic sciences Genetic markers Genetic testing Genotype Genotypes Genotyping Haplotypes - genetics High-Throughput Nucleotide Sequencing - methods Humanities and Social Sciences Humans Laboratories Linkage analysis Linkage disequilibrium Linkage Disequilibrium - genetics Microsatellite Repeats - genetics multidisciplinary Next-generation sequencing Nucleotide sequence Polymorphism, Single Nucleotide - genetics Probability Science Science (multidisciplinary) Sequence Analysis, DNA - methods Short tandem repeats
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