Study of Structural stability and formation mechanisms in DSPC and DPSM liposomes: A coarse-grained molecular dynamics simulation

Liposomes or biological vesicles can be created from cholesterol, phospholipid, and water. Their stability is affected by their phospholipid composition which can influence disease treatment and drug delivery efficacy. In this study, the effect of phospholipid type on the formation and stability of...

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Veröffentlicht in:	Scientific reports 2020-02, Vol.10 (1), p.1837, Article 1837
Hauptverfasser:	Hashemzadeh, H., Javadi, H., Darvishi, M. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	119/118 13/109 14/35 14/5 38/71 42/44 631/114/2397 631/57/2266 639/705/1042 639/925/350/2093 639/925/357/341 Air Pressure Cholesterol Drug delivery Electrostatic properties Energy Energy Metabolism Humanities and Social Sciences Laboratory tests Lipids Liposomes Liposomes - metabolism Medical treatment Micelles Molecular dynamics multidisciplinary Nanostructures Phosphatidylcholines - metabolism Phosphocholine Phospholipid composition Phospholipids Science Science (multidisciplinary) Simulation Sphingomyelin Sphingomyelins - metabolism Static Electricity Temperature
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