Quantification of HER1, HER2 and HER3 by time-resolved Förster resonance energy transfer in FFPE triple-negative breast cancer samples

Background Triple-negative breast cancer (TNBC) has a worse prognosis compared with other breast cancer subtypes, and biomarkers to identify patients at high risk of recurrence are needed. Here, we investigated the expression of human epidermal receptor (HER) family members in TNBC and evaluated the...

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Veröffentlicht in:	British journal of cancer 2020-02, Vol.122 (3), p.397-404
Hauptverfasser:	Ho-Pun-Cheung, Alexandre, Bazin, Hervé, Boissière-Michot, Florence, Mollevi, Caroline, Simony-Lafontaine, Joëlle, Landas, Emeline, Bleuse, Jean-Pierre, Chardès, Thierry, Prost, Jean-François, Pèlegrin, André, Jacot, William, Mathis, Gérard, Lopez-Crapez, Evelyne
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1347 692/53/2422 Adult Aged Aged, 80 and over Biomarkers Biomedical and Life Sciences Biomedicine Breast cancer Cancer Research Carcinoma, Ductal, Breast - metabolism Disease-Free Survival Drug Resistance Epidemiology ErbB Receptors - metabolism ErbB-2 protein Female Fluorescence Resonance Energy Transfer HER protein Humans Immunohistochemistry Life Sciences Medical prognosis Middle Aged Molecular Medicine Neoplasm Recurrence, Local Oncology Paraffin Prognosis Receptor, ErbB-2 - metabolism Receptor, ErbB-3 - metabolism Triple Negative Breast Neoplasms - metabolism Tumors
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