Adipose tissue contribution to plasma fibroblast growth factor 21 and fibroblast activation protein in obesity

Fibroblast growth factor 21 (FGF21) is an important regulator of energy metabolism. FGF21 is inactivated by fibroblast activation protein (FAP). We investigated whether FGF21 and/or FAP are secreted from human white adipose tissue of individuals with obesity by measuring total FGF21, active FGF21, a...

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Veröffentlicht in:	International Journal of Obesity 2020-02, Vol.44 (2), p.544-547
Hauptverfasser:	van Baak, Marleen A., Vink, Roel G., Roumans, Nadia J. T., Cheng, Christine C., Adams, Andrew C., Mariman, Edwin C. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	38 38/61 692/163 692/163/2743/393 Adipose tissue Adipose tissues Adult Blood Body fat Body mass index Body weight loss Brief Communication Diet, Reducing Energy metabolism Epidemiology Fibroblast activation protein Fibroblast growth factors Fibroblast Growth Factors - blood Fibroblasts Gelatinases - blood Gene expression Growth factors Health Promotion and Disease Prevention Humans Ingestion Internal Medicine Medicine Medicine & Public Health Membrane Proteins - blood Metabolic Diseases Obesity Obesity - blood Obesity - diet therapy Obesity - metabolism Physiological aspects Proteins Public Health Serine Endopeptidases - blood Subcutaneous Fat, Abdominal - metabolism Type 2 diabetes Weight control Weight loss Weight reduction
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