IL-27 and TCR Stimulation Promote T Cell Expression of Multiple Inhibitory Receptors

Inhibitory receptors (IR) are a diverse group of cell surface molecules that modulate T cell activation, but there are gaps in our knowledge of the cell-extrinsic factors that regulate their expression. The present study found that in vivo overexpression of IL-27 in mice led to increased T cell expr...

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Veröffentlicht in:ImmunoHorizons 2019-01, Vol.3 (1), p.13-25
Hauptverfasser: DeLong, Jonathan H, O'Hara Hall, Aisling, Rausch, Matt, Moodley, Devapregasan, Perry, Joseph, Park, Jeongho, Phan, Anthony T, Beiting, Daniel P, Kedl, Ross M, Hill, Jonathan A, Hunter, Christopher A
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Sprache:eng
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