KANSL2 and MBNL3 are regulators of pancreatic ductal adenocarcinoma invasion

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal forms of cancer. One major reason for this is that PDAC quickly metastasizes to other organs, thereby making its treatment difficult. The molecular machinery driving PDAC metastasis is still poorly understood. In this study, we applie...

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Veröffentlicht in:	Scientific reports 2020-01, Vol.10 (1), p.1485-1485, Article 1485
Hauptverfasser:	Oladimeji, Peter O., Bakke, Jesse, Wright, William C., Chen, Taosheng
Format:	Artikel
Sprache:	eng
Schlagworte:	13/89 45/41 631/1647/2163 631/67/1504/1713 Adenocarcinoma Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - pathology Cell Line, Tumor Cell Movement - genetics Cell proliferation CRISPR CRISPR-Cas Systems Doxycycline Gene Expression Regulation, Neoplastic Gene Knockout Techniques Histone Acetyltransferases - antagonists & inhibitors Histone Acetyltransferases - genetics Humanities and Social Sciences Humans Metastases multidisciplinary Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Pancreas Pancreatic cancer Pancreatic Neoplasms Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology RNA, Small Interfering - genetics RNA-Binding Proteins - antagonists & inhibitors RNA-Binding Proteins - genetics Science Science (multidisciplinary)
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