The critical role of glucose deprivation in epithelial-mesenchymal transition in hepatocellular carcinoma under hypoxia

Imaging with 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is used to determine sites of abnormal glucose metabolism to predict high tumor grade, metastasis, and poor patient survival. However, not all tumors with increased 18F-FDG uptake show aggressive tumo...

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Veröffentlicht in:	Scientific reports 2020-01, Vol.10 (1), p.1538-1538, Article 1538
Hauptverfasser:	Jo, Hanhee, Lee, Jongsook, Jeon, Jeongyong, Kim, Seon yoo, Chung, Jee-in, Ko, Hae yong, Lee, Misu, Yun, Mijin
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/89 14 14/63 64/60 692/4028/67/322 692/4028/67/327 82/51 Adult Animals Cadherins Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Cell Line, Tumor Cell Movement Cell Proliferation Computed tomography Epithelial-Mesenchymal Transition - physiology Female Fluorodeoxyglucose F18 Gene Expression Regulation, Neoplastic - genetics Glucose Glucose - metabolism Hep G2 Cells Hepatocellular carcinoma Heterogeneity Humanities and Social Sciences Humans Hypoxia Hypoxia - metabolism Hypoxia - physiopathology Liver cancer Liver Neoplasms - metabolism Liver Neoplasms - pathology Male Mesenchyme Metabolism Metastases Metastasis Mice Mice, Inbred BALB C Middle Aged multidisciplinary N-Cadherin Positron emission tomography Positron Emission Tomography Computed Tomography Proliferating cell nuclear antigen Science Science (multidisciplinary) Tomography Tumor Microenvironment - physiology Tumors
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