A bivalent antihypertensive vaccine targeting L‐type calcium channels and angiotensin AT1 receptors

Background and Purpose Hypertension has been the leading preventable cause of premature death worldwide. The aim of this study was to design a more efficient vaccine against novel targets for the treatment of hypertension. Experimental Approach The epitope CE12, derived from the human L‐type calcium...

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Veröffentlicht in:	British journal of pharmacology 2020-01, Vol.177 (2), p.402-419
Hauptverfasser:	Wu, Hailang, Wang, Yiyi, Wang, Gongxin, Qiu, Zhihua, Hu, Xiajun, Zhang, Hongrong, Yan, Xiaole, Ke, Fan, Zou, Anruo, Wang, Min, Liao, Yuhua, Chen, Xiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin AT1 receptors Angiotensin II Antihypertensives Calcium channels Calcium channels (voltage-gated) Channel gating Core protein Epitopes Hepatitis B core antigen Hypertension Immunotherapy Monoclonal antibodies Renin Research Paper Research Papers Vaccines
Online-Zugang:	Volltext
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