Zika virus targets the human thymic epithelium

Previous work showed that the thymus can be infected by RNA viruses as HIV and HTLV-1. We thus hypothesized that the thymus might also be infected by the Zika virus (ZIKV). Herein we provide compelling evidence that ZIKV targets human thymic epithelial cells (TEC) in vivo and in vitro . ZIKV-infecti...

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Veröffentlicht in:	Scientific reports 2020-01, Vol.10 (1), p.1378-1378, Article 1378
Hauptverfasser:	Messias, Carolina V., Loss-Morais, Guilherme, Carvalho, Joseane Biso de, González, Mariela N., Cunha, Daniela P., Vasconcelos, Zilton, Arge, Luis W. P., Farias-de-Oliveira, Désio A., Gerber, Alexandra L., Portari, Elyzabeth A., Ferreira, Nilma, Raphael, Lidiane M. S., Bonaldo, Myrna C., Riederer, Ingo, Lopes Moreira, Maria E., Cotta-de-Almeida, Vinicius, Vasconcelos, Ana T. R., Mendes-da-Cruz, Daniella A., Savino, Wilson
Format:	Artikel
Sprache:	eng
Schlagworte:	38/1 38/39 38/77 631/250/1620 631/250/255/2514 82/51 96/2 96/31 96/63 Animals Cell adhesion Cell adhesion & migration Cell death Cell migration Chlorocebus aethiops Epithelial cells Epithelial Cells - metabolism Epithelial Cells - pathology Epithelial Cells - virology Epithelium Epithelium - metabolism Epithelium - pathology Epithelium - virology HIV Human immunodeficiency virus Humanities and Social Sciences Humans Keratinization Lymphocytes T multidisciplinary RNA viruses Science Science (multidisciplinary) Thymocytes Thymocytes - metabolism Thymocytes - pathology Thymocytes - virology Thymus Thymus Gland - metabolism Thymus Gland - pathology Thymus Gland - virology Vector-borne diseases Vero Cells Viral envelope proteins Viral Tropism Zika virus Zika Virus - physiology Zika Virus Infection - metabolism Zika Virus Infection - pathology
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