Extracellular Nucleotides and P2 Receptors in Renal Function

The understanding of the nucleotide/P2 receptor system in the regulation of renal hemodynamics and transport function has grown exponentially over the last 20 yr. This review attempts to integrate the available data while also identifying areas of missing information. First, the determinants of nucl...

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Veröffentlicht in:	Physiological reviews 2020-01, Vol.100 (1), p.211-269
Hauptverfasser:	Vallon, Volker, Unwin, Robert, Inscho, Edward W, Leipziger, Jens, Kishore, Bellamkonda K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals Autocrine signalling Blood flow Blood pressure Cell membranes Collecting duct Hemodynamics Homeostasis Humans Kidney - metabolism Kidney - physiology Kidney diseases Lithium Nephropathy Nucleotides Nucleotides - metabolism Paracrine signalling Pathophysiology Polycystic kidney Purine P2 receptors Purine P2X receptors Purine P2Y receptors Receptor mechanisms Receptors, Purinergic P2 - metabolism Receptors, Purinergic P2 - physiology Renal function Review Signal Transduction Sodium
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