Andrographolide sodium bisulfate attenuates UV‑induced photo‑damage by activating the keap1/Nrf2 pathway and downregulating the NF‑κB pathway in HaCaT keratinocytes

Oxidative and inflammatory damage has been suggested to play important roles in the pathogenesis of skin photoaging. Andrographolide sodium bisulfate (ASB) is a soluble derivative of andrographolide and has known antioxidant and anti‑inflammatory properties. In the present study, cellular experiment...

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Veröffentlicht in:	International journal of molecular medicine 2020-02, Vol.45 (2), p.343-352
Hauptverfasser:	Wang, Mei-Ling, Zhong, Qing-Yuan, Lin, Bao-Qin, Liu, Yu-Hong, Huang, Yan-Feng, Chen, Yang, Yuan, Jie, Su, Zi-Ren, Zhan, Janis Ya-Xian
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Antioxidants Cytokines Immunoglobulins Inflammation Kinases Oxidative stress Penicillin Reactive oxygen species Signal transduction Skin Tumor necrosis factor-TNF
Online-Zugang:	Volltext
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