Regulation of hippocampal neuronal apoptosis and autophagy in mice with sepsis‐associated encephalopathy by immunity‐related GTPase M1

Aims Sepsis‐associated encephalopathy (SAE) is a common complication of severe sepsis. Our goal was to investigate the role of immunity‐related GTPase M1 (IRGM1) in SAE and its underlying mechanism. Methods A mouse sepsis model was established by cecal ligation and perforation. SAE was diagnosed by...

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Veröffentlicht in:	CNS neuroscience & therapeutics 2020-02, Vol.26 (2), p.177-188
Hauptverfasser:	Zhou, Rui‐Xi, Li, Yu‐Yao, Qu, Yi, Huang, Qun, Sun, Xue‐Mei, Mu, De‐Zhi, Li, Xi‐Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis autophagy immunity‐related GTPase M1 Original p38 mitogen‐activated protein kinase sepsis‐related encephalopathy
Online-Zugang:	Volltext
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