Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states

The sebaceous gland (SG) is an essential component of the skin, and SG dysfunction is debilitating 1 , 2 . Yet, the cellular bases for its origin, development and subsequent maintenance remain poorly understood. Here, we apply large-scale quantitative fate mapping to define the patterns of cell fate...

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Veröffentlicht in:	Nature cell biology 2019-08, Vol.21 (8), p.924-932
Hauptverfasser:	Andersen, Marianne Stemann, Hannezo, Edouard, Ulyanchenko, Svetlana, Estrach, Soline, Antoku, Yasuko, Pisano, Sabrina, Boonekamp, Kim E., Sendrup, Sarah, Maimets, Martti, Pedersen, Marianne Terndrup, Johansen, Jens V., Clement, Ditte L., Feral, Chloe C., Simons, Benjamin D., Jensen, Kim B.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 14/19 631/136/1660/1986 631/532/2118/2438 631/532/2139 631/67/395 64/60 Animal biology Animals Biomedical and Life Sciences Cancer Research Cell Biology Cell division Cell fate Cell Proliferation - physiology Cell research Development Biology Developmental Biology Developmental cytology Disease Progression Fate maps Gene Expression Regulation, Developmental - immunology Health aspects Homeostasis - physiology Letter Life Sciences Mapping Mechanical properties Mice, Transgenic Molecular dynamics Morphogenesis Phase transitions Physiological aspects Sebaceous gland Sebaceous glands Skin Stem Cells Stem Cells - cytology Stochasticity Stroma Tumors Veterinary medicine and animal Health
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