NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk

Multiple schizophrenia (SCZ) risk loci may be involved in gene co-regulation mechanisms, and analysis of coexpressed gene networks may help to clarify SCZ molecular basis. We have previously identified a dopamine D2 receptor ( ) coexpression module enriched for SCZ risk genes and associated with cog...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of neuroscience 2020-01, Vol.40 (4), p.932-941
Hauptverfasser:	Torretta, Silvia, Rampino, Antonio, Basso, Manuela, Pergola, Giulio, Di Carlo, Pasquale, Shin, Joo H, Kleinman, Joel E, Hyde, Thomas M, Weinberger, Daniel R, Masellis, Rita, Blasi, Giuseppe, Pennuto, Maria, Bertolino, Alessandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antipsychotics Binding sites Cognitive ability Computer Simulation Data analysis Dopamine Dopamine D2 receptors Enrichment ERRalpha Estrogen-Related Receptor Gene expression Gene Regulatory Networks Genes Genetic Predisposition to Disease Humans Medical imaging Mental disorders Mice Modules Neuroimaging Neurons - metabolism Nuclear Receptor Subfamily 4, Group A, Member 2 - genetics Nuclear receptors Nurr1 protein Phenotypes Prefrontal cortex Prefrontal Cortex - metabolism Promoter Regions, Genetic Psychotropic drugs Receptors, Dopamine D2 - genetics Receptors, Estrogen - genetics Risk Schizophrenia Schizophrenia - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!