Potential osteomyelitis biomarkers identified by plasma metabolome analysis in mice

Osteomyelitis, which often arises from a surgical-site infection, is a serious problem in orthopaedic surgery. However, there are no specific biomarkers for osteomyelitis. Here, to identify specific plasma biomarkers for osteomyelitis, we conducted metabolome analyses using a mouse osteomyelitis mod...

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Veröffentlicht in:	Scientific reports 2020-01, Vol.10 (1), p.839-839, Article 839
Hauptverfasser:	Isogai, Norihiro, Shiono, Yuta, Kuramoto, Tetsuya, Yoshioka, Kenji, Ishihama, Hiroko, Funao, Haruki, Nakamura, Masaya, Matsumoto, Morio, Ishii, Ken
Format:	Artikel
Sprache:	eng
Schlagworte:	14/5 631/45/320 64/60 692/53/2421 82/58 Animals Bioluminescence Biomarkers Biomarkers - blood Carnitine - analogs & derivatives Carnitine - blood Citric Acid Cycle Disease Models, Animal Fatty acids Fatty Acids - blood Femur Humanities and Social Sciences Ketoglutaric Acids - blood Luminescent Measurements Male Metabolites Metabolome Mice, Inbred BALB C multidisciplinary Osteomyelitis Osteomyelitis - diagnosis Osteomyelitis - etiology Osteomyelitis - microbiology Polyunsaturated fatty acids Principal components analysis Science Science (multidisciplinary) Sphinganine Sphingolipids Sphingolipids - blood Sphingosine - analogs & derivatives Sphingosine - blood Staphylococcal Infections Staphylococcus aureus Succinic acid Succinic Acid - blood Surgery Surgical site infections Surgical Wound Infection - complications Tricarboxylic acid cycle
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