FACTORS ASSOCIATED WITH PERSISTENCE OF HPV GENITAL INFECTION IN A SMALL COHORT OF ROMANIAN WOMEN
The aim of the study was to assess the role of behavioral factors in persistence of human papillomavirus (HPV) genital infection. Out of a cohort of 605 women included in a study of HPV infection prevalence, 142 HPV positive women (aged 18-57) were retested after a 12-month interval. None of the pat...
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| Veröffentlicht in: | Acta clinica Croatica (Tisak) 2019-09, Vol.58 (3), p.410-416 |
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| container_title | Acta clinica Croatica (Tisak) |
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| creator | Huică, Irina Iancu, Iulia Virginia Botezatu, Anca Pleşa, Adriana Socolov, Demetra Teleman, Sergiu Anton, Gabriela |
| description | The aim of the study was to assess the role of behavioral factors in persistence of human papillomavirus (HPV) genital infection. Out of a cohort of 605 women included in a study of HPV infection prevalence, 142 HPV positive women (aged 18-57) were retested after a 12-month interval. None of the patients underwent surgical treatment during that period. Selected patients were asked for a second smear for cytologic analysis and HPV genotyping. A questionnaire that included information regarding reproductive health, sexual activity and smoking status was filled-in. After 12 months, 46 of 142 (32.39%) women had persistent HPV infection, with genotypes 16 and 18 found in 27 cases. On the other hand, 17 of 142 (11.97%) women had acquired new infections replacing the baseline genotypes. In our study, smoking (OR=2.320, p=0.0330) and sexual behavior (OR=5.333, p=0.0180 for more than three sexual partners; OR=2.427, p=0.0238 for cases where the partner was involved in another sexual relationship) were associated with viral persistence, while long-term contraception did not yield statistically significant results. |
| doi_str_mv | 10.20471/acc.2019.58.03.02 |
| format | Article |
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Out of a cohort of 605 women included in a study of HPV infection prevalence, 142 HPV positive women (aged 18-57) were retested after a 12-month interval. None of the patients underwent surgical treatment during that period. Selected patients were asked for a second smear for cytologic analysis and HPV genotyping. A questionnaire that included information regarding reproductive health, sexual activity and smoking status was filled-in. After 12 months, 46 of 142 (32.39%) women had persistent HPV infection, with genotypes 16 and 18 found in 27 cases. On the other hand, 17 of 142 (11.97%) women had acquired new infections replacing the baseline genotypes. In our study, smoking (OR=2.320, p=0.0330) and sexual behavior (OR=5.333, p=0.0180 for more than three sexual partners; OR=2.427, p=0.0238 for cases where the partner was involved in another sexual relationship) were associated with viral persistence, while long-term contraception did not yield statistically significant results.</description><identifier>ISSN: 0353-9466</identifier><identifier>ISSN: 1333-9451</identifier><identifier>EISSN: 1333-9451</identifier><identifier>DOI: 10.20471/acc.2019.58.03.02</identifier><identifier>PMID: 31969751</identifier><language>eng</language><publisher>Croatia: Sestre Milosrdnice University Hospital and Institute of Clinical Medical Research, Vinogradska cesta c. 29 Zagreb</publisher><subject>Adult ; Cohort Studies ; Female ; Genital Diseases, Female - diagnosis ; Genital Diseases, Female - epidemiology ; Genital Diseases, Female - psychology ; Humans ; Middle Aged ; Original Scientific Papers ; Papillomaviridae - isolation & purification ; Papillomavirus Infections - diagnosis ; Papillomavirus Infections - epidemiology ; Papillomavirus Infections - psychology ; Prevalence ; Risk Factors ; Romania - epidemiology ; Sexual Behavior ; Sexual Partners ; Sexually Transmitted Diseases - diagnosis ; Sexually Transmitted Diseases - epidemiology ; Sexually Transmitted Diseases - psychology ; Smoking - epidemiology</subject><ispartof>Acta clinica Croatica (Tisak), 2019-09, Vol.58 (3), p.410-416</ispartof><rights>2019 Sestre Milosrdnice University Hospital</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c402t-6b836a03a373c335fe1f8f61bebdadc9205e414f7252ffa2b20c7452e2d5ab263</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971790/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971790/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31969751$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Huică, Irina</creatorcontrib><creatorcontrib>Iancu, Iulia Virginia</creatorcontrib><creatorcontrib>Botezatu, Anca</creatorcontrib><creatorcontrib>Pleşa, Adriana</creatorcontrib><creatorcontrib>Socolov, Demetra</creatorcontrib><creatorcontrib>Teleman, Sergiu</creatorcontrib><creatorcontrib>Anton, Gabriela</creatorcontrib><title>FACTORS ASSOCIATED WITH PERSISTENCE OF HPV GENITAL INFECTION IN A SMALL COHORT OF ROMANIAN WOMEN</title><title>Acta clinica Croatica (Tisak)</title><addtitle>Acta Clin Croat</addtitle><description>The aim of the study was to assess the role of behavioral factors in persistence of human papillomavirus (HPV) genital infection. Out of a cohort of 605 women included in a study of HPV infection prevalence, 142 HPV positive women (aged 18-57) were retested after a 12-month interval. None of the patients underwent surgical treatment during that period. Selected patients were asked for a second smear for cytologic analysis and HPV genotyping. A questionnaire that included information regarding reproductive health, sexual activity and smoking status was filled-in. After 12 months, 46 of 142 (32.39%) women had persistent HPV infection, with genotypes 16 and 18 found in 27 cases. On the other hand, 17 of 142 (11.97%) women had acquired new infections replacing the baseline genotypes. In our study, smoking (OR=2.320, p=0.0330) and sexual behavior (OR=5.333, p=0.0180 for more than three sexual partners; OR=2.427, p=0.0238 for cases where the partner was involved in another sexual relationship) were associated with viral persistence, while long-term contraception did not yield statistically significant results.</description><subject>Adult</subject><subject>Cohort Studies</subject><subject>Female</subject><subject>Genital Diseases, Female - diagnosis</subject><subject>Genital Diseases, Female - epidemiology</subject><subject>Genital Diseases, Female - psychology</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Original Scientific Papers</subject><subject>Papillomaviridae - isolation & purification</subject><subject>Papillomavirus Infections - diagnosis</subject><subject>Papillomavirus Infections - epidemiology</subject><subject>Papillomavirus Infections - psychology</subject><subject>Prevalence</subject><subject>Risk Factors</subject><subject>Romania - epidemiology</subject><subject>Sexual Behavior</subject><subject>Sexual Partners</subject><subject>Sexually Transmitted Diseases - diagnosis</subject><subject>Sexually Transmitted Diseases - epidemiology</subject><subject>Sexually Transmitted Diseases - psychology</subject><subject>Smoking - epidemiology</subject><issn>0353-9466</issn><issn>1333-9451</issn><issn>1333-9451</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUU1PwkAQ3RiNIvoHPJg9eqHuR7cfF5NNbaFJ6ZK2ynHdLlvFAMUWTPz3FkGip3mTee_NZB4ANxhZBNkuvldadwj7FvMsRC1ETkAPU0oHvs3wKeghynbYcS7AZdu-o67HjJ2DC4p9x3cZ7oGXiAeFyHLI81wEMS_CRziNixGchFke50WYBiEUERxNnuEwTOOCJzBOozAoYpF2CHKYj3mSwECMRFbsqJkY8zTmKZyKcZhegbNKLVpzfah98BSFRTAaJGIYBzwZaBuRzcApPeooRBV1qaaUVQZXXuXg0pQzNdM-QczY2K5cwkhVKVISpF2bEUNmTJXEoX3wsPddb8ulmWmz2jRqIdfNfKmaL1mrufw_Wc3f5Gv9KbtHYNdHncHdwaCpP7am3cjlvNVmsVArU29bSahtE-J7yO2oZE_VTd22jamOazCSP9HILhq5i0YyTyIqEelEt38PPEp-s6DfLY2DAw</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Huică, Irina</creator><creator>Iancu, Iulia Virginia</creator><creator>Botezatu, Anca</creator><creator>Pleşa, Adriana</creator><creator>Socolov, Demetra</creator><creator>Teleman, Sergiu</creator><creator>Anton, Gabriela</creator><general>Sestre Milosrdnice University Hospital and Institute of Clinical Medical Research, Vinogradska cesta c. 29 Zagreb</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20190901</creationdate><title>FACTORS ASSOCIATED WITH PERSISTENCE OF HPV GENITAL INFECTION IN A SMALL COHORT OF ROMANIAN WOMEN</title><author>Huică, Irina ; Iancu, Iulia Virginia ; Botezatu, Anca ; Pleşa, Adriana ; Socolov, Demetra ; Teleman, Sergiu ; Anton, Gabriela</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c402t-6b836a03a373c335fe1f8f61bebdadc9205e414f7252ffa2b20c7452e2d5ab263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Cohort Studies</topic><topic>Female</topic><topic>Genital Diseases, Female - diagnosis</topic><topic>Genital Diseases, Female - epidemiology</topic><topic>Genital Diseases, Female - psychology</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Original Scientific Papers</topic><topic>Papillomaviridae - isolation & purification</topic><topic>Papillomavirus Infections - diagnosis</topic><topic>Papillomavirus Infections - epidemiology</topic><topic>Papillomavirus Infections - psychology</topic><topic>Prevalence</topic><topic>Risk Factors</topic><topic>Romania - epidemiology</topic><topic>Sexual Behavior</topic><topic>Sexual Partners</topic><topic>Sexually Transmitted Diseases - diagnosis</topic><topic>Sexually Transmitted Diseases - epidemiology</topic><topic>Sexually Transmitted Diseases - psychology</topic><topic>Smoking - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Huică, Irina</creatorcontrib><creatorcontrib>Iancu, Iulia Virginia</creatorcontrib><creatorcontrib>Botezatu, Anca</creatorcontrib><creatorcontrib>Pleşa, Adriana</creatorcontrib><creatorcontrib>Socolov, Demetra</creatorcontrib><creatorcontrib>Teleman, Sergiu</creatorcontrib><creatorcontrib>Anton, Gabriela</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Acta clinica Croatica (Tisak)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huică, Irina</au><au>Iancu, Iulia Virginia</au><au>Botezatu, Anca</au><au>Pleşa, Adriana</au><au>Socolov, Demetra</au><au>Teleman, Sergiu</au><au>Anton, Gabriela</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>FACTORS ASSOCIATED WITH PERSISTENCE OF HPV GENITAL INFECTION IN A SMALL COHORT OF ROMANIAN WOMEN</atitle><jtitle>Acta clinica Croatica (Tisak)</jtitle><addtitle>Acta Clin Croat</addtitle><date>2019-09-01</date><risdate>2019</risdate><volume>58</volume><issue>3</issue><spage>410</spage><epage>416</epage><pages>410-416</pages><issn>0353-9466</issn><issn>1333-9451</issn><eissn>1333-9451</eissn><abstract>The aim of the study was to assess the role of behavioral factors in persistence of human papillomavirus (HPV) genital infection. Out of a cohort of 605 women included in a study of HPV infection prevalence, 142 HPV positive women (aged 18-57) were retested after a 12-month interval. None of the patients underwent surgical treatment during that period. Selected patients were asked for a second smear for cytologic analysis and HPV genotyping. A questionnaire that included information regarding reproductive health, sexual activity and smoking status was filled-in. After 12 months, 46 of 142 (32.39%) women had persistent HPV infection, with genotypes 16 and 18 found in 27 cases. On the other hand, 17 of 142 (11.97%) women had acquired new infections replacing the baseline genotypes. 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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Adult Cohort Studies Female Genital Diseases, Female - diagnosis Genital Diseases, Female - epidemiology Genital Diseases, Female - psychology Humans Middle Aged Original Scientific Papers Papillomaviridae - isolation & purification Papillomavirus Infections - diagnosis Papillomavirus Infections - epidemiology Papillomavirus Infections - psychology Prevalence Risk Factors Romania - epidemiology Sexual Behavior Sexual Partners Sexually Transmitted Diseases - diagnosis Sexually Transmitted Diseases - epidemiology Sexually Transmitted Diseases - psychology Smoking - epidemiology |
| title | FACTORS ASSOCIATED WITH PERSISTENCE OF HPV GENITAL INFECTION IN A SMALL COHORT OF ROMANIAN WOMEN |
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