The protective role of MiR-206 in regulating cardiomyocytes apoptosis induced by ischemic injury by targeting PTP1B

MicroRNAs play essential roles in the regulation and pathophysiology of acute myocardial infarction (AMI). The purpose of the present study was to assess the expression signature of miR-206 in rat heart with AMI and the corresponding molecular mechanism. The expression of miR-206 significantly decre...

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Veröffentlicht in:	Bioscience reports 2020-01, Vol.40 (1)
Hauptverfasser:	Yan, Yejun, Dang, Hongwei, Zhang, Xin, Wang, Xia, Liu, Xiaodong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cardiovascular System & Vascular Biology Cell Hypoxia Cells, Cultured Disease Models, Animal Gene Expression & Regulation Gene Expression Regulation, Enzymologic Male MicroRNAs - genetics MicroRNAs - metabolism Molecular Bases of Health & Disease Myocardial Infarction - enzymology Myocardial Infarction - genetics Myocardial Infarction - pathology Myocytes, Cardiac - enzymology Myocytes, Cardiac - pathology Protein Tyrosine Phosphatase, Non-Receptor Type 1 - genetics Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism Rats, Sprague-Dawley Signal Transduction
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