Ruscogenin induces ferroptosis in pancreatic cancer cells

Pancreatic cancer is characterized by aggressive and highly metastatic phenotypes. This disease exhibits a poor patient prognosis and is considered a challenge due to the limited treatment options encountered in clinical practice. Previous studies have shown that ruscogenin, a saponin found in the r...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncology reports 2020-02, Vol.43 (2), p.516-524
Hauptverfasser:	Song, Zhiwang, Xiang, Xiaojun, Li, Junhe, Deng, Jun, Fang, Ziling, Zhang, Ling, Xiong, Jianping
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antineoplastic Agents, Phytogenic - administration & dosage Antineoplastic Agents, Phytogenic - pharmacology Apoptosis Biochemistry Bromine compounds Cancer cells Cancer metastasis Cancer research Cancer therapies Cancer treatment Cell death Cell Line, Tumor Cell Survival - drug effects Chinese medicine Diseases Dose-Response Relationship, Drug Female Ferric oxide Ferroptosis Flow cytometry Gene Expression Regulation, Neoplastic - drug effects Genes Humans Immunoglobulins Iron compounds Medical prognosis Metastasis Mice Nanoparticles Pancreatic cancer Pancreatic Neoplasms - drug therapy Pancreatic Neoplasms - metabolism Phenotypes Prognosis Proteins Reactive oxygen species Reactive Oxygen Species - metabolism Signal Transduction - drug effects Spirostans - administration & dosage Spirostans - pharmacology Time Toxicity Transferrin Tumors Variance analysis Xenograft Model Antitumor Assays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!